TDP1 抗体 (AA 1-608)
(5 references)Quick Overview for TDP1 抗体 (AA 1-608) (ABIN565920)
抗原
See all TDP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-608
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原理
- Mouse polyclonal antibody raised against a full-length recombinant TDP1.
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序列
- MSQEGDYGRW TISSSDESEE EKPKPDKPST SSLLCARQGA ANEPRYTCSE AQKAAHKRKI SPVKFSNTDS VLPPKRQKSG SQEDLGWCLS SSDDELQPEM PQKQAEKVVI KKEKDISAPN DGTAQRTENH GAPACHRLKE EEDEYETSGE GQDIWDMLDK GNPFQFYLTR VSGVKPKYNS GALHIKDILS PLFGTLVSSA QFNYCFDVDW LVKQYPPEFR KKPILLVHGD KREAKAHLHA QAKPYENISL CQAKLDIAFG THHTKMMLLL YEEGLRVVIH TSNLIHADWH QKTQGIWLSP LYPRIADGTH KSGESPTHFK ADLISYLMAY NAPSLKEWID VIHKHDLSET NVYLIGSTPG RFQGSQKDNW GHFRLKKLLK DHASSMPNAE SWPVVGQFSS VGSLGADESK WLCSEFKESM LTLGKESKTP GKSSVPLYLI YPSVENVRTS LEGYPAGGSL PYSIQTAEKQ NWLHSYFHKW SAETSGRSNA MPHIKTYMRP SPDFSKIAWF LVTSANLSKA AWGALEKNGT QLMIRSYELG VLFLPSAFGL DSFKVKQKFF AGSQEPMATF PVPYDLPPEL YGSKDRPWIW NIPYVKAPDT HGNMWVPS
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交叉反应
- 人
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产品特性
- Antibody Reactive Against Recombinant Protein.
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免疫原
- TDP1 (AAH15474.1, 1 a.a. ~ 608 a.a) full-length recombinant protein with GST tag.
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anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibody
TDP1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-260) antibodyTDP1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) antibodyTDP1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibodyTDP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A10-G2 unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-140) antibodyTDP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (Internal Region) antibodyVerified TDP1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 350-399) antibodyTDP1 适用: 人, 小鼠, 马, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-298) antibodyTDP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT1F2 unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 4-215) antibodyTDP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 50 % glycerol
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注意事项
- Aliquot to avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "PARP1-TDP1 coupling for the repair of topoisomerase I-induced DNA damage." in: Nucleic acids research, Vol. 42, Issue 7, pp. 4435-49, (2014) (PubMed).
: "Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes." in: Nature neuroscience, Vol. 17, Issue 6, pp. 813-21, (2014) (PubMed).
: "In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation." in: DNA repair, Vol. 8, Issue 5, pp. 654-63, (2009) (PubMed).
: "Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK." in: The EMBO journal, Vol. 28, Issue 23, pp. 3667-80, (2009) (PubMed).
: "TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo." in: The EMBO journal, Vol. 26, Issue 22, pp. 4720-31, (2007) (PubMed).
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: "PARP1-TDP1 coupling for the repair of topoisomerase I-induced DNA damage." in: Nucleic acids research, Vol. 42, Issue 7, pp. 4435-49, (2014) (PubMed).
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- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
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别名
- TDP1
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背景
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Full Gene Name: tyrosyl-DNA phosphodiesterase 1
Synonyms: FLJ11090,MGC104252 -
基因ID
- 55775
抗原
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