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AGO2 抗体 (AA 1-377)

Name: AGO2 抗体 (AA 1-377)
SKU: ABIN565346
Availability: OutOfStock

This anti-AGO2 antibody is a 小鼠单克隆 antibody detecting AGO2 in WB, ELISA, IF, IHC (p) 和 RNAi. Suitable for 人. This Primary Antibody has been cited in 44+ publications.

Western blot analysis of EIF2C2 over-expressed 293 cell line, cotransfected with EIF2C2 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). (AGO2 抗体 (AA 1-377))

Immunoperoxidase of monoclonal antibody to EIF2C2 on formalin-fixed paraffin-embedded human stomach. (AGO2 抗体 (AA 1-377))

ISt

Immunofluorescence of monoclonal antibody to EIF2C2 on HeLa cell. (AGO2 抗体 (AA 1-377))

Detection limit for recombinant GST tagged EIF2C2 is 0. (AGO2 抗体 (AA 1-377))

ELISA

Western Blot detection against Immunogen (68. (AGO2 抗体 (AA 1-377))

Western Blot analysis of EIF2C2 expression in transfected 293T cell line by EIF2C2 monoclonal antibody (M01), clone 2E12-1C9. (AGO2 抗体 (AA 1-377))

EIF2C2 monoclonal antibody (M01), clone 2E12-1C9. (AGO2 抗体 (AA 1-377))

7 images

(44 references)

产品编号 ABIN565346

发货至: 中国

Quick Overview for AGO2 抗体 (AA 1-377) (ABIN565346)

抗原

See all AGO2 抗体

AGO2 (Argonaute 2 (AGO2))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This AGO2 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

克隆位点

2E12-1C9

抗原表位
8

7

1

1

1

1

1

1

1

1
AA 1-377

原理

Mouse monoclonal antibody raised against a full length recombinant EIF2C2.

序列

MPIQGQPCFC KYAQGADSVE PMFRHLKNTY AGLQLVVVIL PGKTPVYAEV KRVGDTVLGM ATQCVQMKNV QRTTPQTLSN LCLKINVKLG GVNNILLPQG RPPVFQQPVI FLGADVTHPP AGDGKKPSIA AVVGSMDAHP NRYCATVRVQ QHRQEIIQDL AAMVRELLIQ FYKSTRFKPT RIIFYRDGVS EGQFQQVLHH ELLAIREACI KLEKDYQPGI TFIVVQKRHH TRLFCTDKNE RVGKSGNIPA GTTVDTKITH PTEFDFYLCS HAGIQGTSRP SHYHVLWDDN RFSSDELQIL TYQLCHTYVR CTRSVSIPAP AYYAHLVAFR ARYHLVDKEH DSAEGSHTSG QSNGRDHQAL AKAVQVHQDT LRTMYFA

交叉反应

人

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

EIF2C2 (AAH07633.1, 483 a.a. ~ 859 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG1
anti-Argonaute 2 (AGO2) (AA 517-818) antibody
AGO2 适用: 人 WB, ELISA, IHC, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Argonaute 2 (AGO2) antibody
AGO2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Argonaute 2 (AGO2) (AA 1-100) antibody
AGO2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Argonaute 2 (AGO2) (N-Term) antibody
AGO2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Argonaute 2 (AGO2) (AA 47-115) antibody
AGO2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Argonaute 2 (AGO2) (AA 27-59), (N-Term) antibody
AGO2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB8013 unconjugated

anti-Argonaute 2 (AGO2) (AA 1-377) antibody
AGO2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Argonaute 2 (AGO2) (AA 381-480) antibody
AGO2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H2 unconjugated

anti-Argonaute 2 (AGO2) (AA 431-530) antibody
AGO2 适用: 小鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Argonaute 2 (AGO2) antibody
AGO2 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IHC (p), IF (cc) 宿主: 兔 Monoclonal 7C3 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Mantel, Hjelmqvist, Walch, Kharoubi-Hess, Nilsson, Ravel, Ribeiro, Grüring, Ma, Padmanabhan, Trachtenberg, Ankarklev, Brancucci, Huttenhower, Duraisingh, Ghiran, Kuo, Filgueira, Martinelli, Marti: "Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria." in: Nature communications, Vol. 7, pp. 12727, (2016) (PubMed).

Wang, Ye, Wei, Han, He, Chen, Chen: "LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner." in: Journal of hematology & oncology, Vol. 9, Issue 1, pp. 117, (2016) (PubMed).

Xiao, Wang, Ni, Li, Zhang, Liu, Pu, Xu, Gao, Zhao, Mu, Wang, Sun, Du, Xu, Zhang, Hiscox, Goodfellow, Zhou: "MicroRNA miR-24-3p Promotes Porcine Reproductive and Respiratory Syndrome Virus Replication through Suppression of Heme Oxygenase-1 Expression." in: Journal of virology, Vol. 89, Issue 8, pp. 4494-503, (2015) (PubMed).

Zhang, Guo, Gao, Huang, Li, Jia, Liu, Feng: "MicroRNA-23 inhibits PRRSV replication by directly targeting PRRSV RNA and possibly by upregulating type I interferons." in: Virology, Vol. 450-451, pp. 182-95, (2014) (PubMed).

Nakanishi, Taccioli, Palatini, Fernandez-Cymering, Cui, Kim, Volinia, Croce: "Loss of miR-125b-1 contributes to head and neck cancer development by dysregulating TACSTD2 and MAPK pathway." in: Oncogene, Vol. 33, Issue 6, pp. 702-12, (2014) (PubMed).

Sasaki, Gross, Xing, Goshima, Bassell: "Identification of axon-enriched microRNAs localized to growth cones of cortical neurons." in: Developmental neurobiology, Vol. 74, Issue 3, pp. 397-406, (2014) (PubMed).

Pai, Siripornmongcolchai, Berentsen, Pakzad, Vieuille, Pallesen, Pajak, Simpson, Armstrong, Wibrand, Bramham: "NMDA receptor-dependent regulation of miRNA expression and association with Argonaute during LTP in vivo." in: Frontiers in cellular neuroscience, Vol. 7, pp. 285, (2014) (PubMed).

Le Guillou, Marthey, Laloë, Laubier, Mobuchon, Leroux, Le Provost: "Characterisation and comparison of lactating mouse and bovine mammary gland miRNomes." in: PLoS ONE, Vol. 9, Issue 3, pp. e91938, (2014) (PubMed).

Zhang, Zuo, Yang, Li, Xue, Zhou, Huang, Zhao, Zhou, Yan, Zhang, Guo, Sun, Guo, Zhang, Fu: "MicroRNA directly enhances mitochondrial translation during muscle differentiation." in: Cell, Vol. 158, Issue 3, pp. 607-19, (2014) (PubMed).

Kamel, Segerman, Punga, Akusjärvi: "Small RNA sequence analysis of adenovirus VA RNA-derived miRNAs reveals an unexpected serotype-specific difference in structure and abundance." in: PLoS ONE, Vol. 9, Issue 8, pp. e105746, (2014) (PubMed).

Llobet-Navas, Rodriguez-Barrueco, de la Iglesia-Vicente, Olivan, Castro, Saucedo-Cuevas, Marshall, Putcha, Castillo-Martin, Bardot, Ezhkova, Iavarone, Cordon-Cardo, Silva: "The microRNA 424/503 cluster reduces CDC25A expression during cell cycle arrest imposed by transforming growth factor ? in mammary epithelial cells." in: Molecular and cellular biology, Vol. 34, Issue 23, pp. 4216-31, (2014) (PubMed).

Xue, Ouyang, Huang, Zhou, Ouyang, Li, Wang, Wu, Wei, Bi, Jiang, Cai, Sun, Zhang, Zhang, Chen, Fu: "Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits." in: Cell, Vol. 152, Issue 1-2, pp. 82-96, (2013) (PubMed).

Wei, Nazari-Jahantigh, Chan, Zhu, Heyll, Corbalán-Campos, Hartmann, Thiemann, Weber, Schober: "The microRNA-342-5p fosters inflammatory macrophage activation through an Akt1- and microRNA-155-dependent pathway during atherosclerosis." in: Circulation, Vol. 127, Issue 15, pp. 1609-19, (2013) (PubMed).

Laffont, Corduan, Plé, Duchez, Cloutier, Boilard, Provost: "Activated platelets can deliver mRNA regulatory Ago2•microRNA complexes to endothelial cells via microparticles." in: Blood, Vol. 122, Issue 2, pp. 253-61, (2013) (PubMed).

Zheng, Zhang, Zhang, Wang, Ye, Xi, Du, Liang: "Single modification at position 14 of siRNA strand abolishes its gene-silencing activity by decreasing both RISC loading and target degradation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 10, pp. 4017-26, (2013) (PubMed).

Curtale, Mirolo, Renzi, Rossato, Bazzoni, Locati: "Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 28, pp. 11499-504, (2013) (PubMed).

Karginov, Hannon: "Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates." in: Genes & development, Vol. 27, Issue 14, pp. 1624-32, (2013) (PubMed).

Fan, Krutilina, Sun, Sethuraman, Yang, Wu, Yue, Pfeffer: "Comprehensive analysis of microRNA (miRNA) targets in breast cancer cells." in: The Journal of biological chemistry, Vol. 288, Issue 38, pp. 27480-93, (2013) (PubMed).

Martinez-Sanchez, Dudek, Murphy: "Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145)." in: The Journal of biological chemistry, Vol. 287, Issue 2, pp. 916-24, (2012) (PubMed).

Chiang, Sung, Rice: "Regulation of cyclin T1 and HIV-1 Replication by microRNAs in resting CD4+ T lymphocytes." in: Journal of virology, Vol. 86, Issue 6, pp. 3244-52, (2012) (PubMed).

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抗原

AGO2 (Argonaute 2 (AGO2))

别名

EIF2C2

背景

Full Gene Name: eukaryotic translation initiation factor 2C, 2
Synonyms: AGO2,MGC3183,Q10

基因ID

27161

途径

Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization