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GPI 抗体 (AA 5-39)

This 兔 多克隆 anti-GPI antibody specifically detects GPI in WB. The antibody is reactive with 人 samples.
产品编号 ABIN5647569
发货至: 中国
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Quick Overview for GPI 抗体 (AA 5-39) (ABIN5647569)

抗原

See all GPI 抗体
GPI (Glucose-6-Phosphate Isomerase (GPI))

适用

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宿主

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克隆类型

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多克隆

标记

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This GPI antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 5-39

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids 5-39 (TRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNH) from the human protein were used as the immunogen for the GPI antibody.

    亚型

    IgG
  • 应用备注

    Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the GPI antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    GPI (Glucose-6-Phosphate Isomerase (GPI))

    别名

    GPI / Glucose-6-phosphate isomerase

    背景

    Glucose-6-phosphate isomerase (GPI), alternatively known as phosphoglucose isomerase (PGI) or phosphohexose isomerase(PHI), is an enzyme that in humans is encoded by the GPI gene on chromosome 19. This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phophsate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants.

    UniProt

    P06744
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