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APC2 抗体 (AA 51-90)

APC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647467
发货至: 中国
  • 抗原 See all APC2 抗体
    APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
    抗原表位
    • 15
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-90
    适用
    • 28
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 27
    • 1
    克隆类型
    • 27
    • 1
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APC2 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 10
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids 51-90 (KHLQGKLEQEARVLVSSGQTEVLEQLKALQMDITSLYNLK) from the human protein were used as the immunogen for the APC2 antibody.
    亚型
    IgG
    Top Product
    Discover our top product APC2 Primary Antibody
  • 应用备注
    Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the APC2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
    别名
    APC2 (APC2 产品)
    别名
    APCL antibody, AI852447 antibody, R75424 antibody, APC2, WNT signaling pathway regulator antibody, adenomatosis polyposis coli 2 antibody, APC2 antibody, Apc2 antibody
    背景
    APC2, also called APCL or Adenomatous polyposis coli protein-like, is a deduced 2,303-amino acid protein that contains an N-terminal coiled-coil domain, followed by an armadillo domain and five 20-amino acid repeats. The human APC2 gene is mapped to chromosome 19p13.3. It is found that the 20-amino acid repeat domain of APCL could bind beta-catenin (CTNNB1) and deplete the intracellular beta-catenin pool. A reporter gene assay revealed that APCL could regulate interaction of beta-catenin with T cell-specific transcription factors (TCF7), although less efficiently than APC.
    UniProt
    O95996
    途径
    WNT signaling
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