APRT 抗体 (AA 5-49)
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Quick Overview for APRT 抗体 (AA 5-49) (ABIN5647397)
抗原
See all APRT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-49
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 5-49 (ELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARH-human) were used as the immunogen for the APRT antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the APRT antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the APRT antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- APRT (Adenine Phosphoribosyltransferase (APRT))
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别名
- APRT
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背景
- Adenine phosphoribosyltransferase (APRTase) is an enzyme encoded by the APRT gene, found in humans on chromosome 16. It belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P07741
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途径
- Ribonucleoside Biosynthetic Process
抗原
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