NOS1 抗体 (AA 1402-1434)
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Quick Overview for NOS1 抗体 (AA 1402-1434) (ABIN5647390)
抗原
See all NOS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1402-1434
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交叉反应 (详细)
- Expected species reactivity: Human
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 1402-1434 (VTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS) from the human protein were used as the immunogen for the NOS1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the NOS1 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the NOS1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
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别名
- nNOS / NOS1
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背景
- Nitric oxide synthase 1 (neuronal), also known as NOS1, is an enzyme that in humans is encoded by the NOS1 gene. The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.
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UniProt
- P29475
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途径
- Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
抗原
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