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NOS2 抗体 (AA 1088-1126)

This anti-NOS2 antibody is a 兔 多克隆 antibody detecting NOS2 in WB. Suitable for 人.
产品编号 ABIN5647389
发货至: 中国

Quick Overview for NOS2 抗体 (AA 1088-1126) (ABIN5647389)

抗原

See all NOS2 抗体
NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

适用

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宿主

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克隆类型

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多克隆

标记

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This NOS2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    AA 1088-1126

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids 1088-1126 (ARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHED) from the human protein were used as the immunogen for the iNOS antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the iNOS antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the iNOS antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

    别名

    iNOS / NOS2

    背景

    Nitric oxide synthase, inducible is an enzyme that in humans is encoded by the NOS2 gene. Nitric oxide (NO) is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter, it is implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. Three different NOS isoforms have been identified which fall into two distinct types, constitutive and inducible. The inducible NOS (iNOS) isoform is expressed in a variety of cell types and tissues in response to inflammatory agents and cytokines. The human iNOS (NOS2) gene is approximately 37 kb in length and consists of 26 exons and 25 introns. NOS2-derived NO is a prerequisite for cytokine signaling and function in innate immunity.

    UniProt

    P35228

    途径

    Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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