Endoglin 抗体 (AA 258-297)
Our Local Distributor
北京 101111
Quick Overview for Endoglin 抗体 (AA 258-297) (ABIN5647366)
抗原
See all Endoglin (ENG) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 258-297
-
纯化方法
- Antigen affinity purified
-
免疫原
- Amino acids 258-297 (YVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQ) from the human protein were used as the immunogen for the Endoglin antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the Endoglin antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL
-
限制
- 仅限研究用
-
-
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- -20 °C
-
储存方法
- After reconstitution, the Endoglin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
-
- Endoglin (ENG)
-
别名
- CD105 / Endoglin
-
背景
- Endoglin (Osler-Rendu-Weber syndrome 1), also called CD105, is a type I membrane glycoprotein located on cell surfaces and is a part of the TGF beta receptor complex. Its gene is mapped to human chromosome 8. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts and smooth muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling and has been found to be elevated in pregnant women who subsequently develop preeclampsia.
-
UniProt
- P17813
抗原
-