TREM1 抗体
Quick Overview for TREM1 抗体 (ABIN5647283)
抗原
See all TREM1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity purified
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免疫原
- A recombinant mouse protein corresponding to amino acids A21-S202 was used as the immunogen for the Trem1 antibody.
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亚型
- IgG
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anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-205) antibody
TREM1 适用: 人, 大鼠, 猴 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6B12D1 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-205) antibodyTREM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-205) antibodyTREM1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5F9F7 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-230) antibodyTREM1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-234) antibodyTREM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 74-90) antibodyTREM1 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-234) antibodyTREM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) antibodyTREM1 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal TREM-37 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) antibodyTREM1 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6B1 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) antibody (PE)TREM1 适用: 人 FACS 宿主: 小鼠 Monoclonal 6B1 PE
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应用备注
- Optimal dilution of the Trem1 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture, recombinant mouse protein): 0.1-0.5 μg/mL (BSA-free format available)
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Trem1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
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别名
- Trem1
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背景
- Trem1, Triggering receptor expressed on myeloid cells-1, is encoded by TREM1 gene. The expression of Trem1 is in monocytes and neutrophils but not in lymphocytes, dendritic cells, or other cell types. Trem1 is a 30-kD glycoprotein that is reduced to 26 kD by deglycosylation, in agreement with the predicted molecular mass. The Trem1 gene which contains 4 exons maps to chromosome 6p21.1, within a TREM gene cluster and the mouse Trem1 gene maps to chromosome 17 in a region that shows homology of synteny to human chromosome 6. The expression of Trem1 is upregulated by stimulation with lipopolysaccharide (LPS), gram-negative bacteria, and fungi. Cross-linking of Trem1 on neutrophils induces interleukin-8 (IL8) and myeloperoxidase secretion, while cross-linking on monocytes induces not only secretion of IL8 but also of monocyte chemotactic protein-1 (MCP1, or SCYA2) and tumor necrosis factor (TNF), MCP1 and TNF secretion could be further upregulated by LPS-mediated priming. Trem1 engagement also induces upregulation of adhesion molecules (e.g., ITGB1) and costimulatory molecules (e.g., CD40). Trem1 is associated with DAP12 (TYROBP), a molecule frequently associated with activating receptors.
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UniProt
- Q9JKE2
抗原
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