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TREM1 抗体

TREM1 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6B1 unconjugated
产品编号 ABIN7505920
发货至: 中国
  • 抗原 See all TREM1 抗体
    TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
    适用
    • 63
    • 45
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    宿主
    • 73
    • 16
    • 8
    小鼠
    克隆类型
    • 75
    • 21
    单克隆
    标记
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    This TREM1 antibody is un-conjugated
    应用范围
    • 88
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    • 15
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    Western Blotting (WB), Flow Cytometry (FACS), ELISA
    原理
    Anti-Hu CD354 Purified
    特异性
    The mouse monoclonal antibody 6B1 (also known as 6B1.1G12) recognizes an extracellular epitope of human CD354 (TREM-1), a transmembrane glycoprotein, serving as an important innate immunity receptor.
    纯化方法
    Purified by protein-A affinity chromatography.
    免疫原
    recombinant human CD354 fused with IgG
    克隆位点
    6B1
    亚型
    IgG1
    Top Product
    Discover our top product TREM1 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
    别名
    CD354 (TREM1 产品)
    别名
    TREM1 antibody, CD354 antibody, TREM-1 antibody, triggering receptor expressed on myeloid cells 1 antibody, TREM1 antibody, Trem1 antibody, LOC100349504 antibody
    背景
    Triggering receptor expressed on myeloid cells 1,CD354 (TREM-1), a cell surface glycoprotein expressed mainly on monocytes, macrophages, and neutrophils, but also on e.g. endothelial cells or bronchial epithelium, plays an important role in innate immune responses. Upon triggering by its ligands (mainly bacterial and fungal components, but also some viruses, such as Marburg or Ebola virus), it initiates signaling cascades leading to release of pro-inflammatory cytokines and chemokines. CD354 is strongly present in infectious inflammatory lesions (e.g. in folliculitis or impetigo), but not so much in non-infectious inflammatory lesions, (e.g. vasculitis or psoriasis). However, under certain conditions neutrophils can upregulate CD354 also under non-infectious inflammatory conditions, e.g. in rheumatoid arthritis. Soluble CD354 (sTREM-1) is an important biomarker for identification of septic patients, as well as for prediction of their survival.,TREM-1
    基因ID
    54210
    UniProt
    Q9NP99
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