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FGL2 抗体 (AA 24-123)

Name: FGL2 抗体 (AA 24-123)
SKU: ABIN564725
Availability: OutOfStock

This anti-FGL2 antibody is a 小鼠单克隆 antibody detecting FGL2 in WB, ELISA, IP 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 11+ publications.

Western Blot detection against Immunogen (36. (FGL2 抗体 (AA 24-123))

Immunoperoxidase of monoclonal antibody to FGL2 on formalin-fixed paraffin-embedded human stomach. (FGL2 抗体 (AA 24-123))

ISt

FGL2 monoclonal antibody (M01), clone 6D9 Western Blot analysis of FGL2 expression in HeLa . (FGL2 抗体 (AA 24-123))

Western Blot analysis of FGL2 expression in transfected 293T cell line by FGL2 monoclonal antibody (M01), clone 6D9. (FGL2 抗体 (AA 24-123))

Detection limit for recombinant GST tagged FGL2 is approximately 0. (FGL2 抗体 (AA 24-123))

ELISA

FGL2 monoclonal antibody (M01), clone 6D9. (FGL2 抗体 (AA 24-123))

Immunoprecipitation of FGL2 transfected lysate using anti-FGL2 monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with FGL2 MaxPab rabbit polyclonal antibody. (FGL2 抗体 (AA 24-123))

7 images

(11 references)

产品编号 ABIN564725

发货至: 中国

Quick Overview for FGL2 抗体 (AA 24-123) (ABIN564725)

抗原

See all FGL2 抗体

FGL2 (Fibrinogen-Like 2 (FGL2))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This FGL2 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

6D9

抗原表位
16

11

8

7

3

3

3

2

1

1

1

1

1

1

1

1

1
AA 24-123

原理

Mouse monoclonal antibody raised against a partial recombinant FGL2.

序列

NNETEEIKDE RAKDVCPVRL ESRGKCEEAG ECPYQVSLPP LTIQLPKQFS RIEEVFKEVQ NLKEIVNSLK KSCQDCKLQA DDNGDPGRNG LLLPSTGAPG

交叉反应

人, 小鼠, 大鼠

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

FGL2 (NP_006673, 24 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG2a
anti-Fibrinogen-Like 2 (FGL2) (AA 24-123) antibody
FGL2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5A10 unconjugated

anti-Fibrinogen-Like 2 (FGL2) (AA 1-439) antibody
FGL2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Fibrinogen-Like 2 (FGL2) (AA 338-367), (C-Term) antibody
FGL2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB19509 unconjugated

anti-Fibrinogen-Like 2 (FGL2) (AA 75-150) antibody
FGL2 适用: 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Fibrinogen-Like 2 (FGL2) (AA 20-432) antibody
FGL2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fibrinogen-Like 2 (FGL2) (AA 24-439) antibody
FGL2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fibrinogen-Like 2 (FGL2) antibody
FGL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fibrinogen-Like 2 (FGL2) (AA 24-439) antibody
FGL2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fibrinogen-Like 2 (FGL2) (AA 20-432) antibody
FGL2 适用: 小鼠 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated

anti-Fibrinogen-Like 2 (FGL2) (Middle Region) antibody
FGL2 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, Cow, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Long, You, Li, Jin, Huang, Li, Liu, Wang: "Sodium tanshinone IIA sulfonate ameliorates experimental coronary no-reflow phenomenon through down-regulation of FGL2." in: Life sciences, Vol. 142, pp. 8-18, (2015) (PubMed).

Dong, Ye, Chen, Chen, Xie, Li, Lin, Huang: "Intestinal and peripheral fibrinogen-like protein 2 expression in inflammatory bowel disease." in: Digestive diseases and sciences, Vol. 59, Issue 4, pp. 769-77, (2014) (PubMed).

Li, Wang, Long, Su, Bukhory, Dai, Jin, Huang, Jia, Li, Fan, Liu, Wang: "Novel antibody against a glutamic acid-rich human fibrinogen-like protein 2-derived peptide near Ser91 inhibits hfgl2 prothrombinase activity." in: PLoS ONE, Vol. 9, Issue 4, pp. e94551, (2014) (PubMed).

Sun, Xi, Ding, Wang, Zhou, Ning: "Soluble FGL2, a novel effector molecule of activated hepatic stellate cells, regulates T-cell function in cirrhotic patients with hepatocellular carcinoma." in: Hepatology international, Vol. 8, Issue 4, pp. 567-575, (2014) (PubMed).

Xu, Chen, Yang, Li, Zheng, Wu: "C5a/C5aR pathway is essential for the pathogenesis of murine viral fulminant hepatitis by way of potentiating Fgl2/fibroleukin expression." in: Hepatology (Baltimore, Md.), Vol. 60, Issue 1, pp. 114-24, (2014) (PubMed).

Xi, Wang, Ye, Luo, Ning: "Combined adenovirus-mediated artificial microRNAs targeting mfgl2, mFas, and mTNFR1 protect against fulminant hepatic failure in mice." in: PLoS ONE, Vol. 8, Issue 11, pp. e82330, (2013) (PubMed).

Ye, Huai, Chen, Ding, Chen, Cai: "Correlation of fibrinogen-like protein 2 with disease progression in patients with severe acute pancreatitis." in: Experimental and therapeutic medicine, Vol. 7, Issue 1, pp. 85-89, (2013) (PubMed).

Selzner, Liu, Boehnert, Adeyi, Shalev, Bartczak, Xue-Zhong, Manuel, Rotstein, McGilvray, Grant, Phillips, Levy, Selzner: "FGL2/fibroleukin mediates hepatic reperfusion injury by induction of sinusoidal endothelial cell and hepatocyte apoptosis in mice." in: Journal of hepatology, Vol. 56, Issue 1, pp. 153-9, (2011) (PubMed).

Liu, Xu, Xiao, Xiong, Wang, Gao, Yan, Ning: "The FGL2/fibroleukin prothrombinase is involved in alveolar macrophage activation in COPD through the MAPK pathway." in: Biochemical and biophysical research communications, Vol. 396, Issue 2, pp. 555-61, (2010) (PubMed).

OBrien, Morrison, Smith: "Expression of prothrombin and protease activated receptors in human myometrium during pregnancy and labor." in: Biology of reproduction, Vol. 78, Issue 1, pp. 20-6, (2007) (PubMed).

Shalev, Liu, Koscik, Bartczak, Javadi, Wong, Maknojia, He, Liu, Diao, Winter, Manuel, McCarthy, Cattral, Gommerman, Clark, Phillips, Gorczynski, Zhang, Downey, Grant, Cybulsky, Levy: "Targeted deletion of fgl2 leads to impaired regulatory T cell activity and development of autoimmune glomerulonephritis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 1, pp. 249-60, (2007) (PubMed).
抗原

FGL2 (Fibrinogen-Like 2 (FGL2))

别名

FGL2

背景

Full Gene Name: fibrinogen-like 2
Synonyms: T49,pT49

基因ID

10875

NCBI登录号

NM_006682