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PPL 抗体 (AA 1664-1701)

This 兔 多克隆 antibody specifically detects PPL in WB 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN5647242
发货至: 中国
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Quick Overview for PPL 抗体 (AA 1664-1701) (ABIN5647242)

抗原

See all PPL 抗体
PPL (Periplakin (PPL))

适用

  • 31
  • 8
  • 6
  • 1
人, 小鼠, 大鼠

宿主

  • 31
  • 2

克隆类型

  • 33
多克隆

标记

  • 24
  • 3
  • 2
  • 2
  • 1
  • 1
This PPL antibody is un-conjugated

应用范围

  • 30
  • 20
  • 10
  • 6
  • 6
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1664-1701

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids 1664-1701 (DTGRELSPEEAHRAGLIDWNMFVKLRSQECDWEEISVK) from the human protein were used as the immunogen for the Periplakin antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Periplakin antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Periplakin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    PPL (Periplakin (PPL))

    别名

    Periplakin

    背景

    Periplakin is a protein that in humans is encoded by the PPL gene. The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.

    UniProt

    O60437
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