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KIT Ligand 抗体

This anti-KIT Ligand antibody is a 兔 多克隆 antibody detecting KIT Ligand in WB, IHC (p) 和 ELISA (Capture). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5647180
发货至: 中国

Quick Overview for KIT Ligand 抗体 (ABIN5647180)

抗原

See all KIT Ligand (KITLG) 抗体
KIT Ligand (KITLG)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This KIT Ligand antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Capture)
  • 纯化方法

    Antigen affinity purified

    免疫原

    A recombinant human protein corresponding to amino acids E26-A190 was used as the immunogen for the SCF antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the SCF antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ELISA (Capture, human recombinant protein): 0.1-0.5 μg/mL (BSA-free format available)

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the SCF antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    KIT Ligand (KITLG)

    别名

    SCF / KITLG

    背景

    Stem Cell Factor (also known as SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kit receptor (CD117). The SCF gene is mapped to 12q21.32. SCF can exist both as a transmembrane protein and a soluble protein. This cytokine plays an important role in hematopoiesis (formation of blood cells), spermatogenesis, and melanogenesis. SCF may be used along with other cytokines to culture HSCs and hematopoietic progenitors. The expansion of these cells ex-vivo (outside the body) would allow advances in bone-marrow transplantation, in which HSCs are transferred to a patient to re-establish blood formation. One of the problems of injecting SCF for therapeutic purposes is that SCF activates mast cells. The injection of SCF has been shown to cause allergic-like symptoms and the proliferation of mast cells and melanocytes.

    UniProt

    P21583

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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