Superoxide dismutase copper chaperone 抗体 (AA 174-209)
Quick Overview for Superoxide dismutase copper chaperone 抗体 (AA 174-209) (ABIN5647094)
抗原
See all Superoxide dismutase copper chaperone (CCS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 174-209
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 174-209 (DADGRAIFRMEDEQLKVWDVIGRSLIIDEGEDDLGR) from the human protein were used as the immunogen for the CCS antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CCS antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the CCS antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))
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别名
- CCS / Copper chaperone for superoxide dismutase
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背景
- Copper chaperone for superoxide dismutase (CCS, SOD4) is a metalloprotein that is responsible for the delivery of Cu to superoxide dismutase (SOD1). In humans the protein is encoded by the CCS gene. And this gene is mapped to chromosome 11q13 by fluorescence in situ hybridization. The CCS protein is present in mammals and most eukaryotes including yeast. The structure of CCS is composed of three distinct domains that are necessary for its function. Although CCS is important for many organisms, there are CCS independent pathways for SOD1, and many species lack CCS all together, such as C. elegans.
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UniProt
- O14618
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途径
- Transition Metal Ion Homeostasis
抗原
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