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MCM7 抗体 (AA 195-319)

This anti-MCM7 antibody is a 小鼠 单克隆 antibody detecting MCM7 in IF, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN5646889
发货至: 中国

Quick Overview for MCM7 抗体 (AA 195-319) (ABIN5646889)

抗原

See all MCM7 抗体
MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MCM7 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

MCM7-1469
  • 抗原表位

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    AA 195-319

    纯化方法

    Purified

    纯度

    Protein G affinity chromatography

    免疫原

    A human partial recombinant protein corresponding to amino acids 195-319 was used as the immunogen for the MCM7 antibody.

    亚型

    IgG2b kappa
  • 应用备注

    Titering of the MCM7 antibody may be required for optimal performance.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunofluorescence: 0.5-1 μg/mL,Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the MCM7 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

    别名

    MCM7

    背景

    MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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