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Topoisomerase I 抗体 (AA 692-765)

Name: Topoisomerase I 抗体 (AA 692-765)
SKU: ABIN563222
Availability: OutOfStock

This anti-Topoisomerase I antibody is a 小鼠单克隆 antibody detecting Topoisomerase I in WB, ELISA 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.

TOP1 monoclonal antibody (M01), clone 1A1. (Topoisomerase I 抗体 (AA 692-765))

Western Blot detection against Immunogen (33. (Topoisomerase I 抗体 (AA 692-765))

Immunoperoxidase of monoclonal antibody to TOP1 on formalin-fixed paraffin-embedded human stomach. (Topoisomerase I 抗体 (AA 692-765))

IHC (fp)

Immunoperoxidase of monoclonal antibody to TOP1 on formalin-fixed paraffin-embedded human hepatocellular carcinoma. (Topoisomerase I 抗体 (AA 692-765))

ISt

Detection limit for recombinant GST tagged TOP1 is approximately 0. (Topoisomerase I 抗体 (AA 692-765))

ELISA

8 images

(1 reference)

产品编号 ABIN563222

发货至: 中国

Quick Overview for Topoisomerase I 抗体 (AA 692-765) (ABIN563222)

抗原

See all Topoisomerase I (TOP1) 抗体

Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This Topoisomerase I antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1A1

抗原表位
11

8

5

3

3

2

2

1

1

1

1

1

1

1
AA 692-765

原理

Mouse monoclonal antibody raised against a partial recombinant TOP1.

序列

QRLEEQLMKL EVQATDREEN KQIALGTSKL NYLDPRITVA WCKKWGVPIE KIYNKTQREK FAWAIDMADE DYEF

交叉反应

人

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

TOP1 (NP_003277, 692 a.a. ~ 765 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG1
anti-Topoisomerase (DNA) I (TOP1) antibody
TOP1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Monoclonal unconjugated

anti-Topoisomerase (DNA) I (TOP1) antibody
TOP1 适用: 人 WB, ELISA, IHC, IP, FACS 宿主: 兔 Monoclonal 6D8 unconjugated Recombinant Antibody

anti-Topoisomerase (DNA) I (TOP1) antibody
TOP1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Topoisomerase (DNA) I (TOP1) (Internal Region) antibody
TOP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Topoisomerase (DNA) I (TOP1) (AA 1-100) antibody
TOP1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Topoisomerase (DNA) I (TOP1) (N-Term) antibody
TOP1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1291CT875-142-166 unconjugated

anti-Topoisomerase (DNA) I (TOP1) antibody
TOP1 适用: 人, 大鼠 WB, FACS 宿主: 小鼠 Monoclonal 1C6 unconjugated

anti-Topoisomerase (DNA) I (TOP1) (AA 358-501) antibody
TOP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Topoisomerase (DNA) I (TOP1) (AA 692-765) antibody
TOP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Topoisomerase (DNA) I (TOP1) (AA 715-765) antibody
TOP1 适用: 人, 小鼠, Cow, 豚鼠, 马, 兔, 犬, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Kobayashi, Aida, Nagaoka, Begum, Kitawaki, Nakata, Stanlie, Doi, Kato, Okazaki, Shinkura, Muramatsu, Kinoshita, Honjo: "AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 52, pp. 22375-80, (2010) (PubMed).
抗原

Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

别名

TOP1

背景

Full Gene Name: topoisomerase (DNA) I
Synonyms: TOPI

基因ID

7150

NCBI登录号

NM_003286

途径

Caspase Cascade in Apoptosis, Stem Cell Maintenance