电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

NOTCH3 抗体 (AA 47-156)

Cited in 7+ publications. This 小鼠 单克隆 anti-NOTCH3 antibody (Clone 1G5) specifically detects NOTCH3 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN562028
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NOTCH3 抗体 (AA 47-156) (ABIN562028)

抗原

See all NOTCH3 抗体
NOTCH3 (Notch 3 (NOTCH3))

适用

  • 58
  • 19
  • 11
  • 1

宿主

  • 43
  • 15
  • 3
  • 1
  • 1
  • 1
  • 1
小鼠

克隆类型

  • 47
  • 19
单克隆

标记

  • 35
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This NOTCH3 antibody is un-conjugated

应用范围

  • 26
  • 25
  • 23
  • 8
  • 7
  • 4
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA

克隆位点

1G5
  • 抗原表位

    • 14
    • 11
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 47-156

    原理

    Mouse monoclonal antibody raised against a partial recombinant NOTCH3.

    序列

    SPCANGGRCT QLPSREAACL CPPGWVGERC QLEDPCHSGP CAGRGVCQSS VVAGTARFSC RCPRGFRGPD CSLPDPCLSS PCAHGARCSV GPDGRFLCSC PPGYQGRSCR

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    NOTCH3 (NP_000426, 47 a.a. ~ 156 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Meng, Zhang, Lee, Wang: "Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling." in: PLoS ONE, Vol. 8, Issue 9, pp. e75808, (2013) (PubMed).

    Watanabe-Hosomi, Watanabe, Tanaka, Nakagawa, Mizuno: "Transendocytosis is impaired in CADASIL-mutant NOTCH3." in: Experimental neurology, Vol. 233, Issue 1, pp. 303-11, (2012) (PubMed).

    Tada, Itoh, Ishii-Watabe, Suzuki, Kawasaki: "Functional analysis of the Notch ligand Jagged1 missense mutant proteins underlying Alagille syndrome." in: The FEBS journal, Vol. 279, Issue 12, pp. 2096-107, (2012) (PubMed).

    Dong, Blaivas, Wang: "Bidirectional encroachment of collagen into the tunica media in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy." in: Brain research, Vol. 1456, pp. 64-71, (2012) (PubMed).

    Lee, Meng, Elmadhoun, Blaivas, Wang: "Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy affecting an African American man: identification of a novel 15-base pair NOTCH3 duplication." in: Archives of neurology, Vol. 68, Issue 12, pp. 1584-6, (2011) (PubMed).

    Meng, Zhang, Hankenson, Wang: "Thrombospondin 2 potentiates notch3/jagged1 signaling." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 7866-74, (2009) (PubMed).

    Park, Shih, Wang: "Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer." in: Cancer research, Vol. 68, Issue 21, pp. 8852-60, (2008) (PubMed).

  • 抗原

    NOTCH3 (Notch 3 (NOTCH3))

    别名

    NOTCH3

    背景

    Full Gene Name: Notch homolog 3 (Drosophila)
    Synonyms: CADASIL,CASIL

    基因ID

    4854

    NCBI登录号

    NM_000435

    途径

    Notch Signaling
You are here: