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SH2D1A 抗体 (AA 1-128)

Cited in 5+ publications. This 小鼠 单克隆 anti-SH2D1A antibody (Clone 1C9) specifically detects SH2D1A in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN561703
发货至: 中国
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中国
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Quick Overview for SH2D1A 抗体 (AA 1-128) (ABIN561703)

抗原

See all SH2D1A 抗体
SH2D1A (SH2 Domain Containing 1A (SH2D1A))

适用

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宿主

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小鼠

克隆类型

  • 50
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单克隆

标记

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This SH2D1A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

1C9
  • 抗原表位

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    AA 1-128

    原理

    Mouse monoclonal antibody raised against a full length recombinant SH2D1A.

    序列

    MDAVAVYHGK ISRETGEKLL LATGLDGSYL LRDSESVPGV YCLCVLYHGY IYTYRVSQTE TGSWSAETAP GVHKRYFRKI KNLISAFQKP DQGIVIPLQY PVEKKSSARS TQGTTGIRED PDVCLKAP

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    SH2D1A (AAH20732, 1 a.a. ~ 128 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Menard, Cantaert, Chamberlain, Tangye, Riminton, Church, Klion, Cunningham-Rundles, Nichols, Meffre: "Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance." in: The Journal of allergy and clinical immunology, Vol. 133, Issue 4, pp. 1149-61, (2014) (PubMed).

    Meazza, Tuberosa, Cetica, Falco, Parolini, Grieve, Griffiths, Sieni, Marcenaro, Micalizzi, Montin, Fagioli, Moretta, Mingari, Moretta, Notarangelo, Bottino, Aricò, Pende: "Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis." in: The Journal of allergy and clinical immunology, Vol. 134, Issue 6, pp. 1381-1387.e7, (2014) (PubMed).

    Palendira, Low, Bell, Ma, Abbott, Phan, Riminton, Choo, Smart, Lougaris, Giliani, Buckley, Grimbacher, Alvaro, Klion, Nichols, Adelstein, Rickinson, Tangye: "Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus." in: The Journal of experimental medicine, Vol. 209, Issue 5, pp. 913-24, (2012) (PubMed).

    Palendira, Low, Chan, Hislop, Ho, Phan, Deenick, Cook, Riminton, Choo, Loh, Alvaro, Booth, Gaspar, Moretta, Khanna, Rickinson, Tangye: "Molecular pathogenesis of EBV susceptibility in XLP as revealed by analysis of female carriers with heterozygous expression of SAP." in: PLoS biology, Vol. 9, Issue 11, pp. e1001187, (2011) (PubMed).

    Ma, Suryani, Avery, Chan, Nanan, Santner-Nanan, Deenick, Tangye: "Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12." in: Immunology and cell biology, Vol. 87, Issue 8, pp. 590-600, (2009) (PubMed).

  • 抗原

    SH2D1A (SH2 Domain Containing 1A (SH2D1A))

    别名

    SH2D1A

    背景

    Full Gene Name: SH2 domain protein 1A
    Synonyms: DSHP,EBVS,FLJ18687,FLJ92177,IMD5,LYP,MTCP1,SAP,XLP,XLPD

    基因ID

    4068

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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