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IRF1 抗体 (AA 216-325)

This 小鼠 单克隆 antibody specifically detects IRF1 in WB 和 ELISA. It exhibits reactivity toward 人. It has been mentioned in 7+ publications
产品编号 ABIN561520
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IRF1 抗体 (AA 216-325) (ABIN561520)

抗原

See all IRF1 抗体
IRF1 (Interferon Regulatory Factor 1 (IRF1))

适用

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  • 63
  • 44
  • 9
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  • 8
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  • 6
  • 5
  • 4
  • 1
  • 1
  • 1

宿主

  • 96
  • 5
  • 1
  • 1
小鼠

克隆类型

  • 78
  • 25
单克隆

标记

  • 49
  • 11
  • 7
  • 3
  • 3
  • 3
  • 3
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  • 3
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
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This IRF1 antibody is un-conjugated

应用范围

  • 87
  • 26
  • 21
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  • 16
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  • 12
  • 6
  • 3
  • 3
  • 1
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Western Blotting (WB), ELISA

克隆位点

2E4
  • 抗原表位

    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 1
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    • 1
    AA 216-325

    原理

    Mouse monoclonal antibody raised against a partial recombinant IRF1.

    序列

    PMPSTSEATT DEDEEGKLPE DIMKLLEQSE WQPTNVDGKG YLLNEPGVQP TSVYGDFSCK EEPEIDSPGG DIGLSLQRVF TDLKNMDATW LDSLLTPVRL PSIQAIPCAP

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    IRF1 (NP_002189, 216 a.a. ~ 325 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Bartlett, Slater, Glanville, Haas, Caramori, Casolari, Clarke, Message, Aniscenko, Kebadze, Zhu, Mallia, Mizgerd, Belvisi, Papi, Kotenko, Johnston, Edwards: "Defining critical roles for NF-?B p65 and type I interferon in innate immunity to rhinovirus." in: EMBO molecular medicine, Vol. 4, Issue 12, pp. 1244-60, (2012) (PubMed).

    Baumjohann, Okada, Ansel: "Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 5, pp. 2089-92, (2011) (PubMed).

    Choi, Kageyama, Eto, Escobar, Johnston, Monticelli, Lao, Crotty: "ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6." in: Immunity, Vol. 34, Issue 6, pp. 932-46, (2011) (PubMed).

    Fazilleau, McHeyzer-Williams, Rosen, McHeyzer-Williams: "The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding." in: Nature immunology, Vol. 10, Issue 4, pp. 375-84, (2009) (PubMed).

    Nurieva, Chung, Martinez, Yang, Tanaka, Matskevitch, Wang, Dong: "Bcl6 mediates the development of T follicular helper cells." in: Science (New York, N.Y.), Vol. 325, Issue 5943, pp. 1001-5, (2009) (PubMed).

    Steffen, MacKay, Kerr, Tsuchiya, Hu, Fox, Dang, Johnston, Oakes, Tchao, Pak, Fields, Kennedy, Kaeberlein: "Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4." in: Cell, Vol. 133, Issue 2, pp. 292-302, (2008) (PubMed).

    Ye, Lista, Lo Coco, Knowles, Offit, Chaganti, Dalla-Favera: "Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma." in: Science (New York, N.Y.), Vol. 262, Issue 5134, pp. 747-50, (1993) (PubMed).

  • 抗原

    IRF1 (Interferon Regulatory Factor 1 (IRF1))

    别名

    IRF1

    背景

    Full Gene Name: interferon regulatory factor 1
    Synonyms: IRF-1,MAR

    基因ID

    3659

    NCBI登录号

    NM_002198

    途径

    Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
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