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MUC1 抗体 (AA 66-175)

This anti-MUC1 antibody is a 小鼠 单克隆 antibody detecting MUC1 in IHC, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN5611324
发货至: 中国

Quick Overview for MUC1 抗体 (AA 66-175) (ABIN5611324)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

克隆位点

3B10B4
  • 抗原表位

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    AA 66-175

    原理

    CD227 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CD227 (AA: 66-175) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    CD227

    背景

    This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

    分子量

    122.1 kDa

    基因ID

    4582

    UniProt

    P15941

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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