BCL2L10 抗体 (AA 31-186)
Quick Overview for BCL2L10 抗体 (AA 31-186) (ABIN5611302)
抗原
See all BCL2L10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 31-186
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原理
- BCL2L10 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human BCL2L10 (AA: 31-186) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
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别名
- BCL2L10
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背景
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The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.
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分子量
- 22 kDa
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UniProt
- Q9HD36
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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