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BCL2L10 抗体

BCL2L10 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856828
发货至: 中国
  • 抗原 See all BCL2L10 抗体
    BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
    适用
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    宿主
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    克隆类型
    • 32
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    多克隆
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    This BCL2L10 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    产品特性
    Rabbit polyclonal antibody to BCL2L10 (BCL2-like 10 (apoptosis facilitator))
    BCL2L10 antibody [N2C2], Internal
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human BCL2L10. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product BCL2L10 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.32 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
    别名
    BCL2 like 10 (BCL2L10 产品)
    别名
    BCL-B antibody, Boo antibody, Diva antibody, AA420380 antibody, AU023065 antibody, C85687 antibody, NR-13 antibody, mcl1l antibody, nr13 antibody, sb:cb78 antibody, BCL2 like 10 antibody, Bcl2-like 10 antibody, BCL2-like 10 (apoptosis facilitator) antibody, BCL2L10 antibody, Bcl2l10 antibody, bcl2l10 antibody
    背景
    The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

    Cellular Localization: Mitochondrion , Nucleus membrane
    分子量
    22 kDa
    基因ID
    10017
    UniProt
    Q9HD36
    途径
    Positive Regulation of Endopeptidase Activity
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