CD276 抗体 (AA 29-466)
Quick Overview for CD276 抗体 (AA 29-466) (ABIN5611271)
抗原
See all CD276 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 29-466
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原理
- B7H3 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human B7H3 (AA: 29-466) expressed in HEK293 cells.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/100 - 1/500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- CD276
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别名
- B7H3
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背景
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The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 57.2 kDa
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UniProt
- Q5ZPR3
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途径
- Cancer Immune Checkpoints
抗原
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