PDGFRA 抗体 (AA 179-361)
(2 references)Quick Overview for PDGFRA 抗体 (AA 179-361) (ABIN5611263)
抗原
See all PDGFRA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 179-361
-
原理
- CD140a Antibody
-
纯化方法
- Purified antibody
-
免疫原
- Purified recombinant fragment of human CD140a (AA: 179-361) expressed in E. Coli.
-
亚型
- IgG2a
-
-
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 361-528) antibody
PDGFRA 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8E12F2 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 331-719) antibodyPDGFRA 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1-210) antibodyPDGFRA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 179-361) antibodyPDGFRA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1A10A8 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 698-727) antibodyPDGFRA 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB11101 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1048-1077) antibodyPDGFRA 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1021-1089) antibodyPDGFRA 适用: 人, 小鼠, 大鼠, 犬 ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1-1089) antibodyPDGFRA 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 25-218) antibodyPDGFRA 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4H1-1C9 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (C-Term) antibodyPDGFRA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "Extracellular Vesicles Derived from Acidified Metastatic Melanoma Cells Stimulate Growth, Migration, and Stemness of Normal Keratinocytes." in: , Vol. 10, Issue 3, (2022) (PubMed).
: "SLURP-1 Controls Growth and Migration of Lung Adenocarcinoma Cells, Forming a Complex With α7-nAChR and PDGFR/EGFR Heterodimer." in: Frontiers in cell and developmental biology, Vol. 9, pp. 739391, (2021) (PubMed).
-
: "Extracellular Vesicles Derived from Acidified Metastatic Melanoma Cells Stimulate Growth, Migration, and Stemness of Normal Keratinocytes." in: , Vol. 10, Issue 3, (2022) (PubMed).
-
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
-
别名
- CD140a
-
背景
-
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
-
分子量
- 122.6 kDa
-
基因ID
- 5156
-
UniProt
- P16234
-
途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
抗原
-
