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MME 抗体 (AA 549-750)

This anti-MME antibody is a 小鼠 单克隆 antibody detecting MME in FACS, WB 和 ELISA. Suitable for 人.
产品编号 ABIN5611260
发货至: 中国

Quick Overview for MME 抗体 (AA 549-750) (ABIN5611260)

抗原

See all MME 抗体
MME (Membrane Metallo-Endopeptidase (MME))

适用

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  • 48
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  • 1
  • 1
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  • 1

宿主

  • 114
  • 112
  • 2
  • 1
小鼠

克隆类型

  • 136
  • 92
  • 2
单克隆

标记

  • 144
  • 20
  • 16
  • 10
  • 7
  • 3
  • 2
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  • 1
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This MME antibody is un-conjugated

应用范围

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  • 102
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  • 17
  • 10
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  • 5
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Flow Cytometry (FACS), Western Blotting (WB), ELISA

克隆位点

6G12E12
  • 抗原表位

    • 10
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    • 8
    • 8
    • 6
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    • 2
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    • 2
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    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 549-750

    原理

    CD10 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CD10 (AA: 549-750) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    MME (Membrane Metallo-Endopeptidase (MME))

    别名

    CD10

    背景

    This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.

    分子量

    85.5 kDa

    基因ID

    4311

    UniProt

    P08473

    途径

    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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