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CD163 抗体 (AA 101-200)

CD163 适用: 人 WB, FACS, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5608766
发货至: 中国
  • 抗原 See all CD163 抗体
    CD163
    抗原表位
    • 15
    • 15
    • 14
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    适用
    • 129
    • 46
    • 29
    • 28
    • 17
    • 5
    • 3
    • 2
    • 1
    • 1
    宿主
    • 109
    • 48
    • 2
    • 1
    克隆类型
    • 92
    • 67
    • 1
    多克隆
    标记
    • 60
    • 16
    • 15
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD163 antibody is un-conjugated
    应用范围
    • 106
    • 69
    • 53
    • 44
    • 26
    • 24
    • 24
    • 24
    • 20
    • 18
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    预测反应
    Mouse,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CD163.
    亚型
    IgG
    Top Product
    Discover our top product CD163 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    CD163
    别名
    CD163 (CD163 产品)
    背景

    Synonyms: Scavenger receptor cysteine-rich type 1 protein M130, CD163, sCD163, M130

    Background: Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.

    基因ID
    9332
    UniProt
    Q86VB7
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