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FGFR2 抗体 (AA 621-723)

Name: FGFR2 抗体 (AA 621-723)
SKU: ABIN560876
Availability: OutOfStock

FGFR2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G3 unconjugated

Western Blot detection against Immunogen (37. (FGFR2 抗体 (AA 621-723))

Immunoperoxidase of monoclonal antibody to FGFR2 on formalin-fixed paraffin-embedded human stomach carcinoma tissue. (FGFR2 抗体 (AA 621-723))

ISt

Detection limit for recombinant GST tagged FGFR2 is approximately 0. (FGFR2 抗体 (AA 621-723))

ELISA

Western Blot analysis of FGFR2 expression in transfected 293T cell line by FGFR2 monoclonal antibody (M01), clone 1G3. (FGFR2 抗体 (AA 621-723))

4 images

(7 references)

产品编号 ABIN560876

发货至: 中国

Datasheet as PDF

抗原 See all FGFR2 抗体

FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
抗原表位
15

11

10

10

9

8

4

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 621-723
适用
115

54

47

9

4

1

1

1

1

1

1

1

1

1
人
宿主
104

9

2

1
小鼠
Compatible Secondaries
克隆类型
94

22
单克隆
标记
59

9

7

5

5

5

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This FGFR2 antibody is un-conjugated
应用范围
73

53

42

40

30

16

12

12

11

9

3

3

2

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Mouse monoclonal antibody raised against a partial recombinant FGFR2.

序列

GHRMDKPANC TNELYMMMRD CWHAVPSQRP TFKQLVEDLD RILTLTTNEE YLDLSQPLEQ YSPSYPDTRS SCSSGDDSVF SPDPMPYEPC LPQYPHINGS VKT

特异性

This antibody cross-reacts with human FGFR1 and human FGFR3.

交叉反应

人

交叉反应（详细）

This antibody cross-reacts with human FGFR1 and human FGFR3.

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

FGFR2 (AAH39243, 621 a.a. ~ 723 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

克隆位点

1G3

亚型

IgG2b

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anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (C-Term) antibody
FGFR2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37), (N-Term) antibody
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anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 794-821) antibody
FGFR2 适用: 人 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (Internal Region) antibody
FGFR2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (Internal Region) antibody
FGFR2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Czaplinska, Mieczkowski, Supernat, Skladanowski, Kordek, Biernat, Zaczek, Romanska, Sadej: "Interactions between FGFR2 and RSK2-implications for breast cancer prognosis." in: Tumour biology, Vol. 37, Issue 10, pp. 13721-13731, (2016) (PubMed).

Katano, Yamada: "Upregulation of ANGPTL4 messenger RNA and protein in severely calcified carotid plaques." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 23, Issue 5, pp. 933-47, (2014) (PubMed).

Lee, Seo, Park, Kim, Park, Yu, Ahn, Gong: "Low prognostic implication of fibroblast growth factor family activation in triple-negative breast cancer subsets." in: Annals of surgical oncology, Vol. 21, Issue 5, pp. 1561-8, (2014) (PubMed).

Cazet, Charest, Bennett, Sambrooks, Contessa: "Mannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity." in: PLoS ONE, Vol. 9, Issue 10, pp. e110345, (2014) (PubMed).

Grygielewicz, Dymek, Bujak, Gunerka, Stanczak, Lamparska-Przybysz, Wieczorek, Dzwonek, Zdzalik: "Epithelial-mesenchymal transition confers resistance to selective FGFR inhibitors in SNU-16 gastric cancer cells." in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, (2014) (PubMed).

Ozawa, Yang, Ealy: "The expression of fibroblast growth factor receptors during early bovine conceptus development and pharmacological analysis of their actions on trophoblast growth in vitro." in: Reproduction (Cambridge, England), Vol. 145, Issue 2, pp. 191-201, (2013) (PubMed).

Vermeulen, Kornegoor, van der Wall, van der Groep, van Diest: "Differential expression of growth factor receptors and membrane-bound tumor markers for imaging in male and female breast cancer." in: PLoS ONE, Vol. 8, Issue 1, pp. e53353, (2013) (PubMed).
抗原

FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

别名

FGFR2 (FGFR2 产品)

背景

Full Gene Name: fibroblast growth factor receptor 2
Synonyms: BEK,BFR-1,CD332,CEK3,CFD1,ECT1,FLJ98662,JWS,K-SAM,KGFR,TK14,TK25

基因ID

2263

途径

RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding