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FGFR2 抗体 (AA 621-723)

This anti-FGFR2 antibody is a 小鼠 单克隆 antibody detecting FGFR2 in WB, ELISA 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 7+ publications.
产品编号 ABIN560876
发货至: 中国

Quick Overview for FGFR2 抗体 (AA 621-723) (ABIN560876)

抗原

See all FGFR2 抗体
FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This FGFR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1G3
  • 抗原表位

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    AA 621-723

    原理

    Mouse monoclonal antibody raised against a partial recombinant FGFR2.

    序列

    GHRMDKPANC TNELYMMMRD CWHAVPSQRP TFKQLVEDLD RILTLTTNEE YLDLSQPLEQ YSPSYPDTRS SCSSGDDSVF SPDPMPYEPC LPQYPHINGS VKT

    特异性

    This antibody cross-reacts with human FGFR1 and human FGFR3.

    交叉反应

    交叉反应 (详细)

    This antibody cross-reacts with human FGFR1 and human FGFR3.

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    FGFR2 (AAH39243, 621 a.a. ~ 723 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Czaplinska, Mieczkowski, Supernat, Skladanowski, Kordek, Biernat, Zaczek, Romanska, Sadej: "Interactions between FGFR2 and RSK2-implications for breast cancer prognosis." in: Tumour biology, Vol. 37, Issue 10, pp. 13721-13731, (2016) (PubMed).

    Katano, Yamada: "Upregulation of ANGPTL4 messenger RNA and protein in severely calcified carotid plaques." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 23, Issue 5, pp. 933-47, (2014) (PubMed).

    Lee, Seo, Park, Kim, Park, Yu, Ahn, Gong: "Low prognostic implication of fibroblast growth factor family activation in triple-negative breast cancer subsets." in: Annals of surgical oncology, Vol. 21, Issue 5, pp. 1561-8, (2014) (PubMed).

    Cazet, Charest, Bennett, Sambrooks, Contessa: "Mannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity." in: PLoS ONE, Vol. 9, Issue 10, pp. e110345, (2014) (PubMed).

    Grygielewicz, Dymek, Bujak, Gunerka, Stanczak, Lamparska-Przybysz, Wieczorek, Dzwonek, Zdzalik: "Epithelial-mesenchymal transition confers resistance to selective FGFR inhibitors in SNU-16 gastric cancer cells." in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, (2014) (PubMed).

    Ozawa, Yang, Ealy: "The expression of fibroblast growth factor receptors during early bovine conceptus development and pharmacological analysis of their actions on trophoblast growth in vitro." in: Reproduction (Cambridge, England), Vol. 145, Issue 2, pp. 191-201, (2013) (PubMed).

    Vermeulen, Kornegoor, van der Wall, van der Groep, van Diest: "Differential expression of growth factor receptors and membrane-bound tumor markers for imaging in male and female breast cancer." in: PLoS ONE, Vol. 8, Issue 1, pp. e53353, (2013) (PubMed).

  • 抗原

    FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

    别名

    FGFR2

    背景

    Full Gene Name: fibroblast growth factor receptor 2
    Synonyms: BEK,BFR-1,CD332,CEK3,CFD1,ECT1,FLJ98662,JWS,K-SAM,KGFR,TK14,TK25

    基因ID

    2263

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
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