我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

CBS 抗体 (AA 1-100)

Name: CBS 抗体 (AA 1-100)
SKU: ABIN7489109
Availability: OutOfStock

Cited in 38+ publications. This 小鼠单克隆 anti-CBS antibody (Clone 3E1) specifically detects CBS in WB, ELISA, IHC (p), IP 和 RNAi. The antibody is reactive with 人 samples.

Western Blot detection against Immunogen (36. (CBS 抗体 (AA 1-100))

Immunoprecipitation of CBS transfected lysate using anti-CBS monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with CBS MaxPab rabbit polyclonal antibody. (CBS 抗体 (AA 1-100))

Immunoperoxidase of monoclonal antibody to CBS on formalin-fixed paraffin-embedded human hepatocellular carcinoma. (CBS 抗体 (AA 1-100))

ISt

CBS monoclonal antibody (M01), clone 3E1 Western Blot analysis of CBS expression in HeLa . (CBS 抗体 (AA 1-100))

Western Blot analysis of CBS expression in transfected 293T cell line by CBS monoclonal antibody (M01), clone 3E1. (CBS 抗体 (AA 1-100))

CBS monoclonal antibody (M01), clone 3E1. (CBS 抗体 (AA 1-100))

Western blot analysis of CBS over-expressed 293 cell line, cotransfected with CBS Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). (CBS 抗体 (AA 1-100))

Detection limit for recombinant GST tagged CBS is approximately 0. (CBS 抗体 (AA 1-100))

ELISA

8 images

(38 references)

产品编号 ABIN7489109

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CBS 抗体 (AA 1-100) (ABIN7489109)

抗原

See all CBS 抗体

CBS (Cystathionine-beta-Synthase (CBS))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This CBS antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), RNA Interference (RNAi)

克隆位点

3E1

抗原表位
15

9

6

6

4

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 1-100

原理

Mouse monoclonal antibody raised against a partial recombinant CBS.

序列

MPSETPQAEV GPTGCPHRSG PHSAKGSLEK GSPEDKEAKE PLWIRPDAPS RCTWQLGRPA SESPHHHTAP AKSPKILPDI LKKIGDTPMV RINKIGKKFG

交叉反应

人, 大鼠

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

CBS (NP_000062, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG2a
anti-Cystathionine-beta-Synthase (CBS) (AA 252-551) antibody
CBS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 104-133), (N-Term) antibody
CBS 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB22961 unconjugated

anti-Cystathionine-beta-Synthase (CBS) antibody
KD Validated CBS 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB3800 unconjugated Recombinant Antibody

anti-Cystathionine-beta-Synthase (CBS) (AA 1-100) antibody
CBS 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6A9 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (N-Term) antibody
CBS 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-413) antibody
CBS 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) antibody
CBS 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) antibody
KO Validated CBS 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 301-330) antibody
CBS 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21183 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-551) antibody
CBS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Shang, Siow, Isaak, O: "Downregulation of Glutathione Biosynthesis Contributes to Oxidative Stress and Liver Dysfunction in Acute Kidney Injury." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 9707292, (2016) (PubMed).

Ohmura, Hishiki, Yamamoto, Nakanishi, Kubo, Tsuchihashi, Tamada, Toue, Kabe, Saya, Suematsu: "Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry." in: Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society, Vol. 46, pp. 102-13, (2015) (PubMed).

Yuan, Tang, Lu, Zhou, Zhu, Zhou, Zhang, Hu, Xu: "TLR4 upregulates CBS expression through NF-κB activation in a rat model of irritable bowel syndrome with chronic visceral hypersensitivity." in: World journal of gastroenterology, Vol. 21, Issue 28, pp. 8615-28, (2015) (PubMed).

Yang, Wu, Wood, Whiteman, Bian: "Hydrogen sulfide attenuates opioid dependence by suppression of adenylate cyclase/cAMP pathway." in: Antioxidants & redox signaling, Vol. 20, Issue 1, pp. 31-41, (2014) (PubMed).

Takano, Peng, Kumar, Luo, Hu, Shimoda, Suematsu, Prabhakar, Semenza: "Hypoxia-inducible factors regulate human and rat cystathionine ?-synthase gene expression." in: The Biochemical journal, Vol. 458, Issue 2, pp. 203-11, (2014) (PubMed).

Takano, Sarfraz, Gilkes, Chaturvedi, Xiang, Suematsu, Zagzag, Semenza: "Decreased expression of cystathionine ?-synthase promotes glioma tumorigenesis." in: Molecular cancer research : MCR, Vol. 12, Issue 10, pp. 1398-406, (2014) (PubMed).

Miyamoto, Otsuguro, Yamaguchi, Ito: "Contribution of cysteine aminotransferase and mercaptopyruvate sulfurtransferase to hydrogen sulfide production in peripheral neurons." in: Journal of neurochemistry, Vol. 130, Issue 1, pp. 29-40, (2014) (PubMed).

Ida, Sawa, Ihara, Tsuchiya, Watanabe, Kumagai, Suematsu, Motohashi, Fujii, Matsunaga, Yamamoto, Ono, Devarie-Baez, Xian, Fukuto, Akaike: "Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 21, pp. 7606-11, (2014) (PubMed).

Du, Jin, Hong, Li, Wang, Xu, Wang, Zhang, Jia, Liu, Hu: "Downregulation of cystathionine ?-synthase/hydrogen sulfide contributes to rotenone-induced microglia polarization toward M1 type." in: Biochemical and biophysical research communications, Vol. 451, Issue 2, pp. 239-45, (2014) (PubMed).

Yamamoto, Takano, Ishiwata, Ohmura, Nagahata, Matsuura, Kamata, Sakamoto, Nakanishi, Kubo, Hishiki, Suematsu: "Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway." in: Nature communications, Vol. 5, pp. 3480, (2014) (PubMed).

Rashid, Heer, Garle, Alexander, Roberts: "Hydrogen sulphide-induced relaxation of porcine peripheral bronchioles." in: British journal of pharmacology, Vol. 168, Issue 8, pp. 1902-10, (2013) (PubMed).

Hwang, Sarna, Siow, O: "High-fat diet stimulates hepatic cystathionine β-synthase and cystathionine γ-lyase expression." in: Canadian journal of physiology and pharmacology, Vol. 91, Issue 11, pp. 913-9, (2013) (PubMed).

Yang, Zhao, Ju, Mani, Cao, Puukila, Khaper, Wu, Wang: "Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2." in: Antioxidants & redox signaling, Vol. 18, Issue 15, pp. 1906-19, (2013) (PubMed).

Shi, Zhang, Xiao, Hu, Xu: "Electroacupuncture suppresses mechanical allodynia and nuclear factor ? B signaling in streptozotocin-induced diabetic rats." in: CNS neuroscience & therapeutics, Vol. 19, Issue 2, pp. 83-90, (2013) (PubMed).

Liu, Luo, Liang, Xia, Xu, Chen, Chen: "Actions of hydrogen sulfide and ATP-sensitive potassium channels on colonic hypermotility in a rat model of chronic stress." in: PLoS ONE, Vol. 8, Issue 2, pp. e55853, (2013) (PubMed).

Zhang, Hu, Zhou, Hu, Wang, Chen, Xiao, Huang, Jiang, Xu: "Promoted interaction of nuclear factor-?B with demethylated cystathionine-?-synthetase gene contributes to gastric hypersensitivity in diabetic rats." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 21, pp. 9028-38, (2013) (PubMed).

Hu, Xu, Miao, Gao, Zhu, Zhou, Xiao, Xu: "Sensitization of sodium channels by cystathionine ?-synthetase activation in colon sensory neurons in adult rats with neonatal maternal deprivation." in: Experimental neurology, Vol. 248, pp. 275-85, (2013) (PubMed).

Kasparek, Linden, Farrugia, Sarr: "Hydrogen sulfide modulates contractile function in rat jejunum." in: The Journal of surgical research, Vol. 175, Issue 2, pp. 234-42, (2012) (PubMed).

Guo, Gai, Wang, Jin, Du, Jin: "Characterization of hydrogen sulfide and its synthases, cystathionine ?-synthase and cystathionine ?-lyase, in human prostatic tissue and cells." in: Urology, Vol. 79, Issue 2, pp. 483.e1-5, (2012) (PubMed).

Dufton, Natividad, Verdu, Wallace: "Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe." in: Scientific reports, Vol. 2, pp. 499, (2012) (PubMed).

show more references
抗原

CBS (Cystathionine-beta-Synthase (CBS))

别名

CBS

背景

Full Gene Name: cystathionine-beta-synthase
Synonyms: HIP4

基因ID

875

NCBI登录号

NM_000071