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JAK2 抗体 (pTyr372)

The 兔 多克隆 anti-JAK2 antibody is suitable to detect JAK2 in samples from 人. It has been validated for WB, IHC 和 ELISA.
Rockland
产品编号 ABIN5596932
Supplier Product No.: 600-401-j46
发货至: 中国
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Quick Overview for JAK2 抗体 (pTyr372) (ABIN5596932)

抗原

See all JAK2 抗体
JAK2 (Janus Kinase 2 (JAK2))

适用

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宿主

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克隆类型

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多克隆

标记

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This JAK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    pTyr372

    Supplier Product No.

    600-401-j46

    Supplier

    Rockland

    原理

    JAK2 phospho Y972 Antibody

    交叉反应 (详细)

    A BLAST analysis was used to suggest cross-reactivity with human, orangutan, rat, and pig based on 100 % sequence homology.

    产品特性

    Synonyms: rabbit anti-JAK2 pY972 antibody, JAK 2, JAK-2, Tyrosine-protein kinase JAK2, Janus kinase 2

    纯化方法

    Anti-JAK II was affinity purified from monospecific antiserum by immunoaffinity chromatography.

    过滤

    Sterile filtered

    免疫原

    Immunogen: JAK II affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the pY372 region of human JAK II.

    Immunogen Type: Conjugated Peptide

    亚型

    IgG
  • 应用备注

    Immunohistochemistry Dilution: User Optimized

    Application Note: Anti-JAK2 antibody is useful for ELISA, immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~130 kDa corresponding to the appropriate cell lysate or extract.

    Western Blot Dilution: 1 μg/mL

    ELISA Dilution: 1: 10,000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.12 mg/mL

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 30 % Glycerol

    Preservative: None

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    JAK2 (Janus Kinase 2 (JAK2))

    别名

    JAK2

    背景

    Background: Janus Kinase 2 (JAK2) antibody is essential for signaling thorough a variety of cytokine receptors. Phosphorylation of JAK is essential for downstream signaling. JAK kinases are known to phosphorylate several substrate including members of the STAT family of proteins. Anti-JAK II antibody is ideal for researchers investigating Cancer, Signal Transduction, Epigenetics and Nuclear Signaling, and Cell Biology research.

    UniProt

    O60674

    途径

    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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