JAK2 抗体 (pTyr372)
Quick Overview for JAK2 抗体 (pTyr372) (ABIN5596932)
抗原
See all JAK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr372
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Supplier Product No.
- 600-401-j46
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Supplier
- Rockland
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原理
- JAK2 phospho Y972 Antibody
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交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with human, orangutan, rat, and pig based on 100 % sequence homology.
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产品特性
- Synonyms: rabbit anti-JAK2 pY972 antibody, JAK 2, JAK-2, Tyrosine-protein kinase JAK2, Janus kinase 2
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纯化方法
- Anti-JAK II was affinity purified from monospecific antiserum by immunoaffinity chromatography.
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过滤
- Sterile filtered
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免疫原
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Immunogen: JAK II affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the pY372 region of human JAK II.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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应用备注
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Immunohistochemistry Dilution: User Optimized
Application Note: Anti-JAK2 antibody is useful for ELISA, immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~130 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1: 10,000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.12 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 30 % Glycerol
Preservative: None -
储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- JAK2 (Janus Kinase 2 (JAK2))
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别名
- JAK2
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背景
- Background: Janus Kinase 2 (JAK2) antibody is essential for signaling thorough a variety of cytokine receptors. Phosphorylation of JAK is essential for downstream signaling. JAK kinases are known to phosphorylate several substrate including members of the STAT family of proteins. Anti-JAK II antibody is ideal for researchers investigating Cancer, Signal Transduction, Epigenetics and Nuclear Signaling, and Cell Biology research.
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UniProt
- O60674
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途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
抗原
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