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HDAC9 抗体 (N-Term)

This anti-HDAC9 antibody is a 兔 多克隆 antibody detecting HDAC9 in WB, IHC 和 ELISA. Suitable for 人.
Rockland
产品编号 ABIN5596729
Supplier Product No.: 600-401-j73
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HDAC9 抗体 (N-Term) (ABIN5596729)

抗原

See all HDAC9 抗体
HDAC9 (Histone Deacetylase 9 (HDAC9))

适用

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宿主

  • 90
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克隆类型

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多克隆

标记

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This HDAC9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    N-Term

    Supplier Product No.

    600-401-j73

    Supplier

    Rockland

    原理

    HDAC9 (N-terminus) Antibody

    交叉反应 (详细)

    A BLAST analysis was used to suggest cross-reactivity with human based on 100 % sequence homology.

    产品特性

    Synonyms: rabbit anti-HDAC-9 antibody, HDAC9, HDAC 9, HD-9, HD 9, Histone deacetylase 9, Histone deacetylase-9, HD9, Histone deacetylase 7B, HD7, HD7b, Histone deacetylase-related protein, MEF2-interacting transcription repressor MITR, HDAC7, HDAC7B, HDRP, MITR

    纯化方法

    Anti-HDAC9 was affinity purified from monospecific antiserum by immunoaffinity chromatography.

    过滤

    Sterile filtered

    免疫原

    Immunogen: Anti-HDAC9 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide at the N-terminal of human HDAC9 protein.

    Immunogen Type: Conjugated Peptide

    亚型

    IgG
  • 应用备注

    Immunohistochemistry Dilution: 5 μg/mL

    Application Note: Anti-HDAC9 antibody is tested by Immunohistochemistry and useful for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~111 kDa corresponding to the appropriate cell lysate or extract.

    Western Blot Dilution: 1 μg/mL

    ELISA Dilution: 1: 10,000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.07 mg/mL

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 30 % Glycerol

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    HDAC9 (Histone Deacetylase 9 (HDAC9))

    别名

    HDAC9

    背景

    Background: HDAC9 is located in the nucleus, expressed most highly in brain, heart, muscle, and testis. It is responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). The result of deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. HDAC9 represses MEF2-dependent transcription by recruiting HDAC1 and 3. It appears to inhibit skeletal myogenesis and be a factor in heart development. By repressing JUN transcription via HDAC1 and inhibiting JUN phosphorylation by MAPK10, HDAC9 protects neurons from apoptosis. Anti-HDAC9 therefore is ideal for investigators interested in Cardiovascular or Epigenetics and Nuclear Signaling research.

    UniProt

    Q9UKV0

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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