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PLG 抗体 (HRP)

PLG 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal HRP
产品编号 ABIN5596692
发货至: 中国
  • 抗原 See all PLG 抗体
    PLG (Plasminogen (PLG))
    适用
    • 95
    • 32
    • 29
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    宿主
    • 82
    • 14
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    • 1
    山羊
    克隆类型
    • 109
    • 7
    多克隆
    标记
    • 70
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    • 1
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    This PLG antibody is conjugated to HRP
    应用范围
    • 82
    • 49
    • 27
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    • 15
    • 14
    • 14
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    • 10
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应 (详细)
    Cross reactivity against Plasminogen from other sources is unknown.
    纯化方法
    Anti-Plasminogen is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti-Goat Serum as well as purified and partially purified Plasminogen [Human Plasma].
    免疫原

    Immunogen: Plasminogen [Human Plasma]

    Immunogen Type: Native Protein

    亚型
    IgG
    Top Product
    Discover our top product PLG Primary Antibody
  • 应用备注

    Immunohistochemistry Dilution: 1:250 - 1:1,000

    Application Note: Anti-Plasminogen has been assayed against 1.0 μg of Plasminogen [Human Plasma] in a standard capture ELISA using ABTS (2,2'-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid]) code # ABTS-100 as a substrate for 30 minutes at room temperature. A working dilution of 1:1,000 to 1:4,000 of the reconstitution concentration is suggested for this product.

    Western Blot Dilution: 1:500 - 1:2,500

    ELISA Dilution: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式

    Reconstitution Volume: 100 μL

    Reconstitution Buffer: Restore with deionized water (or equivalent)

    浓度
    1.0 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

    储存液
    Gentamicin sulfate
    注意事项
    This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    PLG (Plasminogen (PLG))
    别名
    Plasminogen (PLG 产品)
    别名
    wu:fb70e09 antibody, PLG antibody, LPA antibody, plg antibody, Ab1-346 antibody, AI649309 antibody, Pg antibody, plasminogen antibody, plg antibody, PLG antibody, Plg antibody
    背景

    Synonyms: Angiostatin antibody, DKFZp779M0222 antibody, Microplasmin antibody, Plasmin antibody, Plasmin heavy chain A antibody, Plasmin light chain B antibody, PLG antibody

    Background: Plasmin is released as a zymogen called plasminogen (PLG) from the liver into the systemic circulation. Two major glycoforms of plasminogen are present in humans. Type II plasminogen is preferentially recruited to the cell surface over the type I glycoform. Conversely, type I plasminogen appears more readily recruited to blood clots. In circulation, plasminogen adopts a closed, activation resistant conformation. Upon binding to clots, or to the cell surface, plasminogen adopts an open form that can be converted into active plasmin by a variety of enzymes, including tissue plasminogen activator (tPA), urokinase plasminogen activator (uPA), kallikrein, and factor XII (Hageman factor). Fibrin is a cofactor for plasminogen activation by tissue plasminogen activator. Urokinase plasminogen activator receptor (uPAR) is a cofactor for plasminogen activation by urokinase plasminogen activator. The conversion of plasminogen to plasmin involves the cleavage of the peptide bond between Arg-561 and Val-562. Deficiency in plasmin may lead to thrombosis, as clots are not degraded adequately. Plasminogen deficiency in mice leads to defective liver repair, defective wound healing, reproductive abnormalities. In humans, a rare disorder called plasminogen deficiency type I is caused by mutations of the PLG gene and is often manifested by ligneous conjunctivitis.

    Gene Name: PLG

    基因ID
    5340
    UniProt
    P00747
    途径
    Complement System, Lipid Metabolism
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