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APOC3 抗体

APOC3 适用: 人 WB, ELISA, IHC, IP 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN5596680
发货至: 中国
  • 抗原 See all APOC3 抗体
    APOC3 (Apolipoprotein C-III (APOC3))
    适用
    • 47
    • 37
    • 32
    宿主
    • 62
    • 10
    • 5
    山羊
    克隆类型
    • 70
    • 7
    多克隆
    标记
    • 33
    • 10
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APOC3 antibody is un-conjugated
    应用范围
    • 55
    • 32
    • 21
    • 14
    • 14
    • 12
    • 8
    • 8
    • 5
    • 5
    • 4
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    • 2
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    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    交叉反应 (详细)
    Typically less than 1% cross reactivity against other types of apoLipoprotein was detected by ELISA against purified standards. This antibody reacts with human apoLipoprotein C-III and has negligible cross-reactivity with Type A-I, A-II, B, C-I, C-II, E and J apoLipoproteins. Specific cross reaction of anti-apoLipoprotein antibodies with antigens from other species has not been determined. Non-specific cross reaction of anti-apoLipoprotein antibodies with other human serum proteins is negligible.
    纯化方法
    This product has been prepared by immunoaffinity chromatography using immobilized antigens followed by extensive cross-adsorption against other apoLipoproteins and human serum proteins to remove any unwanted specificities.
    免疫原

    Immunogen: produced from apoLipoprotein Type C-III derived from human plasma

    Immunogen Type: Native Protein

    亚型
    IgG
    Top Product
    Discover our top product APOC3 Primary Antibody
  • 应用备注

    Immunohistochemistry Dilution: 1:50 - 1:200

    Application Note: Anti-Apolipoprotein antibodies have been used for indirect trapping ELISA for quantitation of antigen in serum using a standard curve, immunoprecipitation, immunohistochemistry, and for western blotting for highly sensitive qualitative analysis. When performing immunoblotting assays - do not block with blotto. Blotto formulations tend to contain apoLipoprotein Type C-III and will neutralize antibody activity.

    Western Blot Dilution: 1:500 - 1:5,000

    Immunoprecipitation Dilution: 1:100

    ELISA Dilution: 1:5,000 - 1:10,000

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液

    Buffer: 0.125 M Sodium Borate, 0.075 M Sodium Chloride, 0.005 M EDTA, pH 8.0

    Stabilizer: None

    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at 4° C prior to opening. This product is stable 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage mix with an equal volume of glycerol, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing.
    有效期
    12 months
  • Jansen, Cirak, van Scherpenzeel, Timal, Reunert, Rust, Pérez, Vicogne, Krawitz, Wada, Ashikov, Pérez-Cerdá, Medrano, Arnoldy, Hoischen, Huijben, Steenbergen, Quelhas, Diogo, Rymen, Jaeken, Guffon et al.: "CCDC115 Deficiency Causes a Disorder of Golgi Homeostasis with Abnormal Protein Glycosylation. ..." in: American journal of human genetics, Vol. 98, Issue 2, pp. 310-21, (2016) (PubMed).

    Takinami, Yoshimatsu, Uchiumi, Toyosaki-Maeda, Morita, Ishihara, Yamane, Fukuda, Okamoto, Numata, Fukui: "Identification of potential prognostic markers for knee osteoarthritis by serum proteomic analysis." in: Biomarker insights, Vol. 8, pp. 85-95, (2013) (PubMed).

  • 抗原
    APOC3 (Apolipoprotein C-III (APOC3))
    别名
    APOLIPOPROTEINC-III (APOC3 产品)
    别名
    APOC3 antibody, APOCIII antibody, HALP2 antibody, Apoc antibody, ApoC-III antibody, apo-CIII antibody, Apo-CIII antibody, apolipoprotein C3 antibody, apolipoprotein C-III antibody, APOC3 antibody, Apoc3 antibody
    背景

    Synonyms: ApoCIII antibody, Apolipoprotein C III antibody

    Background: Anti Apolipoprotein C-III antibody recognizes the gene product of APOC. Apolipoprotein C-III is a protein component of very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase, it is thought to inhibit hepatic uptake of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia. This antibody is suitable for cardiovascular research.

    Gene Name: APOC3

    基因ID
    345
    UniProt
    P02656
    途径
    Carbohydrate Homeostasis, Lipid Metabolism
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