APOC3 抗体
(2 references)
Quick Overview for APOC3 抗体 (ABIN5596680)
抗原
See all APOC3 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 600-101-114
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Supplier
- Rockland
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原理
- APOLIPOPROTEIN C-III Antibody
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交叉反应 （详细）
- Typically less than 1 % cross reactivity against other types of apoLipoprotein was detected by ELISA against purified standards.
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产品特性
- Synonyms: goat anti-Apolipoprotein C-III antibody, ApoC-III, Apo-CIII antibody, Apolipoprotein C3, Apolipoprotein C III antibody
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纯化方法
- This product has been prepared by immunoaffinity chromatography using immobilized antigens followed by extensive cross-adsorption against other apoLipoproteins and human serum proteins to remove any unwanted specificities.
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过滤
- Sterile filtered
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免疫原
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Immunogen: produced from apoLipoprotein Type C-III derived from human plasma
Immunogen Type: Native Protein
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亚型
- IgG
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anti-Apolipoprotein C-III (APOC3) (AA 1-99) antibody
APOC3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein C-III (APOC3) antibodyAPOC3 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Apolipoprotein C-III (APOC3) antibodyAPOC3 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein C-III (APOC3) (AA 21-99) antibodyAPOC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein C-III (APOC3) (AA 21-99) antibodyAPOC3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 8H7 unconjugated
anti-Apolipoprotein C-III (APOC3) (AA 41-80) antibodyAPOC3 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein C-III (APOC3) (AA 21-99) antibodyAPOC3 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein C-III (APOC3) (AA 21-99) antibodyAPOC3 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein C-III (APOC3) antibodyAPOC3 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 8H12 unconjugated Recombinant Antibody
anti-Apolipoprotein C-III (APOC3) (AA 70-99), (C-Term) antibodyAPOC3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15169 unconjugated
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应用备注
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Immunohistochemistry Dilution: 1:50 - 1:200
Application Note: Anti-Apolipoprotein antibodies have been tested in immunohistochemistry and used for indirect trapping ELISA for quantitation of antigen in serum using a standard curve, immunoprecipitation, immunohistochemistry, and for western blotting for highly sensitive qualitative analysis. When performing immunoblotting assays - do not block with blotto. Blotto formulations tend to contain apoLipoprotein Type C-III and will neutralize antibody activity.
Western Blot Dilution: 1:500 - 1:5,000
Immunoprecipitation Dilution: 1:100
ELISA Dilution: 1:5,000 - 1:10,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: 0.125 M Sodium Borate, 0.075 M Sodium Chloride, 0.005 M EDTA, pH 8.0
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to opening. This product is stable 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage mix with an equal volume of glycerol, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing.
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有效期
- 12 months
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: "CCDC115 Deficiency Causes a Disorder of Golgi Homeostasis with Abnormal Protein Glycosylation. ..." in: American journal of human genetics, Vol. 98, Issue 2, pp. 310-21, (2016) (PubMed).
: "Identification of potential prognostic markers for knee osteoarthritis by serum proteomic analysis." in: Biomarker insights, Vol. 8, pp. 85-95, (2013) (PubMed).
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: "CCDC115 Deficiency Causes a Disorder of Golgi Homeostasis with Abnormal Protein Glycosylation. ..." in: American journal of human genetics, Vol. 98, Issue 2, pp. 310-21, (2016) (PubMed).
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- APOC3 (Apolipoprotein C-III (APOC3))
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别名
- APOC3
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背景
- Background: Anti Apolipoprotein C-III antibody recognizes the gene product of APOC. Apolipoprotein C-III is a protein component of very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase, it is thought to inhibit hepatic uptake of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia. This antibody is suitable for cardiovascular research.
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基因ID
- 345
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UniProt
- P02656
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途径
- Carbohydrate Homeostasis, Lipid Metabolism
抗原
-
