Recombinant Angiopoietin 2 抗体
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- 抗原 See all Angiopoietin 2 (ANGPT2) 抗体
- Angiopoietin 2 (ANGPT2)
- 抗体类型
- Recombinant Antibody
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Angiopoietin 2 antibody is un-conjugated
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应用范围
- ELISA, Functional Studies (Func)
- 特异性
- Recognizes human and mouse angiopoietin-2.
- 交叉反应
- 人, 小鼠
- 交叉反应 （详细）
- Does not detect human angiopoietin-1.
- 纯度
- >95 % (SDS-PAGE)
- 免疫原
- Recombinant human angiopoietin-2.
- 克隆位点
- Angy-2-1
- 亚型
- IgG2b
- Top Product
- Discover our top product ANGPT2 Primary Antibody
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anti-Angiopoietin 2 (ANGPT2) (AA 24-165) antibody
ANGPT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 19-147) antibodyANGPT2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) antibodyANGPT2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (N-Term) antibodyANGPT2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 404-432), (C-Term) antibodyANGPT2 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB17789 unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 401-496) antibodyANGPT2 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 19-485) antibodyANGPT2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 19-483) antibodyANGPT2 适用: 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (N-Term) antibodyANGPT2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (N-Term) antibodyANGPT2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
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- 说明
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anti-Angiopoietin-2, mAb (rec.) (blocking) (Angy-2-1) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the mouse lgG2b Fc domain.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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- 抗原
- Angiopoietin 2 (ANGPT2)
- 别名
- Angiopoietin-2 (ANGPT2 产品)
- 别名
- AGPT2 antibody, ANG2 antibody, Agpt2 antibody, Ang-2 antibody, Ang2 antibody, ang2 antibody, angpt2 antibody, ANGIOPOIETIN-2 antibody, ANG-2 antibody, ANGPT2 antibody, Angrp antibody, Rnase5b antibody, ANG3 antibody, C11orf2 antibody, C11orf3 antibody, FFR antibody, angiopoietin 2 antibody, angiopoietin 2b antibody, angiogenin, ribonuclease A family, member 2 antibody, VPS51, GARP complex subunit antibody, ANGPT2 antibody, Angpt2 antibody, angpt2b antibody, Ang2 antibody, VPS51 antibody
- 背景
- Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context. anti-Angiopoietin-2, mAb (rec.) (blocking) (Angy-2-1) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
- UniProt
- O15123
- 途径
- RTK signaling
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