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Nanog 抗体

This 兔 单克隆 antibody specifically detects Nanog in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN5557500
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Nanog 抗体 (ABIN5557500)

抗原

See all Nanog (NANOG) 抗体
Nanog (NANOG) (Nanog Homeobox (NANOG))

适用

  • 146
  • 58
  • 23
  • 4
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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 137
  • 16
  • 3
  • 1

克隆类型

  • 120
  • 37
单克隆

标记

  • 82
  • 9
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  • 4
  • 3
  • 3
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  • 3
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This Nanog antibody is un-conjugated

应用范围

  • 119
  • 61
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  • 53
  • 34
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  • 26
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  • 16
  • 15
  • 9
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  • 1
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  • 1
Western Blotting (WB)

克隆位点

1A11
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant human Nanog protein, around N-terminal 1-100aa.

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Nanog (NANOG) (Nanog Homeobox (NANOG))

    别名

    Nanog

    背景

    Synonyms: Homeobox protein NANOG, NANOG

    Background: Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation.

    基因ID

    79923

    UniProt

    Q9H9S0

    途径

    Stem Cell Maintenance
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