Recombinant H2AFX 抗体 (pSer139)
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北京 101111
Quick Overview for Recombinant H2AFX 抗体 (pSer139) (ABIN5557485)
抗原
See all H2AFX 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer139
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原理
- Phospho-H2AX (Ser139) Recombinant Antibody
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated Synthesized phosphopeptide derived from human Histone H2A.X around the phosphorylation site of Ser139:QA(p-S)QE.
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亚型
- IgG
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应用备注
- WB(1:500-2000), IHC-P(1:200-1000), IHC-F(1:200-1000), IF(1:200-1000)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- H2AFX (H2A Histone Family, Member X (H2AFX))
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别名
- Histone H2A.X
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背景
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Synonyms: H2A histone family member X, Histone H2A.x, H2afx, H2a.x, H2ax, Hist5-2ax, H2A.X, H2A/X, H2AX, H2AFX, H2AX_HUMAN.
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008].
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基因ID
- 3014
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UniProt
- P16104
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途径
- Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
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