HDAC6 抗体
Quick Overview for HDAC6 抗体 (ABIN5557482)
抗原
See all HDAC6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant human HDAC6 protein, around C-terminal 150aa.
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亚型
- IgG
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anti-Histone Deacetylase 6 (HDAC6) (AA 560-811) antibody
HDAC6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人, 大鼠, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 1-200) antibodyHDAC6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 166-348) antibodyHDAC6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 1128-1215) antibodyHDAC6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人 WB, ELISA, IP, ICC, ICFC 宿主: 小鼠 Monoclonal 236 unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 69-118) antibodyHDAC6 适用: 人, 小鼠, 猴, 兔, 马, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (C-Term) antibodyVerified HDAC6 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人 IF, IP, FACS 宿主: 小鼠 Monoclonal unconjugated
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应用备注
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WB 1:1000-2000
IHC-P 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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别名
- HDAC6
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背景
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Synonyms: HD6, JM21, CPBHM, PPP1R90, Histone deacetylase 6, HDAC6, KIAA0901
Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. In addition to its protein deacetylase activity, plays a key role in the degradation of misfolded proteins: when misfolded proteins are too abundant to be degraded by the chaperone refolding system and the ubiquitin-proteasome, mediates the transport of misfolded proteins to a cytoplasmic juxtanuclear structure called aggresome. Probably acts as an adapter that recognizes polyubiquitinated misfolded proteins and target them to the aggresome, facilitating their clearance by autophagy.
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基因ID
- 10013
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UniProt
- Q9UBN7
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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