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Histone H3.3 抗体

This anti-Histone H3.3 antibody is a 兔 单克隆 antibody detecting Histone H3.3 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN5557308
发货至: 中国

Quick Overview for Histone H3.3 抗体 (ABIN5557308)

抗原

See all Histone H3.3 (H3F3A) 抗体
Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

适用

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宿主

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克隆类型

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单克隆

标记

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This Histone H3.3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

7B12
  • 交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant human Histone H3.3 protein, full length.

    亚型

    IgG
  • 应用备注

    WB 1:300-1000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

    别名

    Histone H3.3

    背景

    Synonyms: H3F3, H3.3A, Histone H3.3, H3F3A, PP781

    Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    基因ID

    3020

    UniProt

    P84243
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