CCR6 抗体
Our Local Distributor
北京 101111
Quick Overview for CCR6 抗体 (ABIN121968)
抗原
See all CCR6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Reacts with C-C Chemokine Receptor 6 (Family: GPCR, Subfamily: Chemokine).
-
纯化方法
- Peptide immunogen affinity column
-
免疫原
- Synthetic peptide - KLH conjugated.
-
-
-
-
应用备注
-
Immunohistochemistry on Paraffin embedded sections: 2-9 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.7, containing 0.01 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-80 °C
-
储存方法
-
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
-
-
-
: "Identification of the Single Immunodominant Region of the Native Human CC Chemokine Receptor 6 Recognized by Mouse Monoclonal Antibodies." in: PLoS ONE, Vol. 11, Issue 6, pp. e0157740, (2017) (PubMed).
-
-
- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
-
别名
- CD196 / CCR6
-
背景
- CCR6 is a Chemokine Receptor that is activated by MIP3alpha/Larc binding. CCR6 has been shown to be upregulated in psoriatic skin. CCR6 has been reported to be expressed in intestine, colon, liver, lymph node, spleen, lung, blood, umbilical cord, placenta, skin, and pancreas. It has also been reported to be expressed in lymphocytes, T cells, and B cells but not in natural killer cells, monocytes, or granulocytes from spleen, lymph node, appendix, and fetal liver. ESTs have been isolated from liver/spleen, lymph, and fetal lung / testis /B cell libraries.Synonyms: C-C CKR-6, C-C chemokine receptor type 6, CC-CKR-6, CCR-6, CKRL3, CMKBR6, Chemokine receptor-like 3, DRY6, G-protein coupled receptor 29, GPR-CY4, GPR29, LARC receptor, STRL22
-
基因ID
- 1235
-
UniProt
- P51684
-
途径
- cAMP Metabolic Process
抗原
-