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CCR6 抗体

Cited in 1 publication. The 兔 多克隆 anti-CCR6 antibody (ABIN121968) specifically detects CCR6 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN121968
发货至: 中国
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Quick Overview for CCR6 抗体 (ABIN121968)

抗原

See all CCR6 抗体
CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

适用

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宿主

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克隆类型

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多克隆

标记

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This CCR6 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    Reacts with C-C Chemokine Receptor 6 (Family: GPCR, Subfamily: Chemokine).

    纯化方法

    Peptide immunogen affinity column

    免疫原

    Synthetic peptide - KLH conjugated.
  • 应用备注

    Immunohistochemistry on Paraffin embedded sections: 2-9 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.7, containing 0.01 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-80 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • Dorgham, Dejou, Piesse, Gorochov, Pène, Yssel: "Identification of the Single Immunodominant Region of the Native Human CC Chemokine Receptor 6 Recognized by Mouse Monoclonal Antibodies." in: PLoS ONE, Vol. 11, Issue 6, pp. e0157740, (2017) (PubMed).

  • 抗原

    CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

    别名

    CD196 / CCR6

    背景

    CCR6 is a Chemokine Receptor that is activated by MIP3alpha/Larc binding. CCR6 has been shown to be upregulated in psoriatic skin. CCR6 has been reported to be expressed in intestine, colon, liver, lymph node, spleen, lung, blood, umbilical cord, placenta, skin, and pancreas. It has also been reported to be expressed in lymphocytes, T cells, and B cells but not in natural killer cells, monocytes, or granulocytes from spleen, lymph node, appendix, and fetal liver. ESTs have been isolated from liver/spleen, lymph, and fetal lung / testis /B cell libraries.Synonyms: C-C CKR-6, C-C chemokine receptor type 6, CC-CKR-6, CCR-6, CKRL3, CMKBR6, Chemokine receptor-like 3, DRY6, G-protein coupled receptor 29, GPR-CY4, GPR29, LARC receptor, STRL22

    基因ID

    1235

    UniProt

    P51684

    途径

    cAMP Metabolic Process
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