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SSH1 抗体 (AA 1032-1044)

SSH1 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6C11G9 unconjugated
产品编号 ABIN5542668
发货至: 中国
  • 抗原 See all SSH1 抗体
    SSH1 (Slingshot Homolog 1 (SSH1))
    抗原表位
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1032-1044
    适用
    • 38
    • 4
    • 2
    • 2
    宿主
    • 24
    • 14
    小鼠
    克隆类型
    • 25
    • 13
    单克隆
    标记
    • 21
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SSH1 antibody is un-conjugated
    应用范围
    • 26
    • 19
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    原理
    SLINGSHOT-1L Antibody
    纯化方法
    Purified antibody
    免疫原
    Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. Coli.
    克隆位点
    6C11G9
    亚型
    IgG1
    Top Product
    Discover our top product SSH1 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    SSH1 (Slingshot Homolog 1 (SSH1))
    别名
    SLINGSHOT-1L (SSH1 产品)
    背景
    The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    分子量
    115.5 kDa
    基因ID
    54434
    UniProt
    Q8WYL5
    途径
    CXCR4-mediated Signaling Events
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