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Caspase 3 抗体 (AA 29-175)

CASP3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D4D10 unconjugated
产品编号 ABIN5542609
发货至: 中国
  • 抗原 See all Caspase 3 (CASP3) 抗体
    Caspase 3 (CASP3)
    抗原表位
    • 20
    • 16
    • 16
    • 14
    • 12
    • 12
    • 10
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-175
    适用
    • 195
    • 115
    • 72
    • 15
    • 9
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 207
    • 22
    • 3
    • 2
    • 2
    小鼠
    克隆类型
    • 203
    • 32
    单克隆
    标记
    • 141
    • 18
    • 17
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Caspase 3 antibody is un-conjugated
    应用范围
    • 171
    • 96
    • 91
    • 59
    • 41
    • 32
    • 29
    • 27
    • 26
    • 26
    • 25
    • 11
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    CASP3 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human CASP3 (AA: 29-175) expressed in E. Coli.
    克隆位点
    3D4D10
    亚型
    IgG1
    Top Product
    Discover our top product CASP3 Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    Caspase 3 (CASP3)
    别名
    CASP3 (CASP3 产品)
    背景

    Description: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

    Aliases: CPP32, SCA-1, CPP32B

    分子量
    31.6kDa
    基因ID
    836
    HGNC
    836
    UniProt
    P42574
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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