PMS2 抗体 (AA 748-851)
Quick Overview for PMS2 抗体 (AA 748-851) (ABIN5542596)
抗原
See all PMS2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 748-851
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原理
- PMS2 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human PMS2 (AA: 748-851) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
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别名
- PMS2
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背景
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This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.
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分子量
- 95.8 kDa
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基因ID
- 5395
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UniProt
- P54278
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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