TdT 抗体 (AA 52-192)
Quick Overview for TdT 抗体 (AA 52-192) (ABIN5542551)
抗原
See all TdT (DNTT) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 52-192
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原理
- DNTT Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human DNTT (AA: 52-192) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
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别名
- DNTT
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背景
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This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
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分子量
- 58.5 kDa
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基因ID
- 1791
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UniProt
- P04053
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途径
- DNA Damage Repair
抗原
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