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DNMT3B 抗体 (AA 1-150)

This anti-DNMT3B antibody is a 小鼠 单克隆 antibody detecting DNMT3B in ELISA, FACS 和 ICC. Suitable for 人.
产品编号 ABIN5542517
发货至: 中国

Quick Overview for DNMT3B 抗体 (AA 1-150) (ABIN5542517)

抗原

See all DNMT3B 抗体
DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

适用

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宿主

  • 93
  • 6
  • 2
  • 1
小鼠

克隆类型

  • 86
  • 16
单克隆

标记

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This DNMT3B antibody is un-conjugated

应用范围

  • 84
  • 39
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  • 2
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  • 1
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ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

4D1A2E5
  • 抗原表位

    • 17
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    • 2
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    • 1
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    • 1
    • 1
    AA 1-150

    原理

    DNMT3B Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human DNMT3B (AA: 1-150) expressed in E. Coli.

    亚型

    IgG2a
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

    别名

    DNMT3B

    背景

    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

    分子量

    95.8 kDa

    基因ID

    1789

    UniProt

    Q9UBC3
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