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DNMT3L 抗体 (AA 147-386)

This anti-DNMT3L antibody is a 小鼠 单克隆 antibody detecting DNMT3L in ELISA 和 FACS. Suitable for 人.
产品编号 ABIN5542515
发货至: 中国

Quick Overview for DNMT3L 抗体 (AA 147-386) (ABIN5542515)

抗原

See all DNMT3L (TRDMT1) 抗体
DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

适用

  • 73
  • 19
  • 4

宿主

  • 70
  • 11
小鼠

克隆类型

  • 72
  • 9
单克隆

标记

  • 38
  • 6
  • 5
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DNMT3L antibody is un-conjugated

应用范围

  • 66
  • 35
  • 17
  • 13
  • 13
  • 7
  • 7
  • 6
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
ELISA, Flow Cytometry (FACS)

克隆位点

2D10H11
  • 抗原表位

    • 15
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-386

    原理

    DNMT3L Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human DNMT3L (AA: 147-386) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

    别名

    DNMT3L

    背景

    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    分子量

    43.6 kDa

    基因ID

    29947

    UniProt

    Q9UJW3
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