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APP 抗体 (AA 483-699)

This anti-APP antibody is a 小鼠 单克隆 antibody detecting APP in ELISA 和 FACS. Suitable for 人.
产品编号 ABIN5542446
发货至: 中国

Quick Overview for APP 抗体 (AA 483-699) (ABIN5542446)

抗原

See all APP 抗体
APP (Amyloid beta (A4) Precursor Protein (APP))

适用

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宿主

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小鼠

克隆类型

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  • 1
单克隆

标记

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This APP antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS)

克隆位点

5H10A10
  • 抗原表位

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    AA 483-699

    原理

    APP Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human APP (AA: 483-699) expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    APP (Amyloid beta (A4) Precursor Protein (APP))

    别名

    APP

    背景

    This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

    分子量

    87 kDa

    基因ID

    351

    UniProt

    P05067

    途径

    Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
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