MIB1 抗体 (AA 6-221)
Quick Overview for MIB1 抗体 (AA 6-221) (ABIN5542433)
抗原
See all MIB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 6-221
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原理
- MIB1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human MIB1 (AA: 6-221) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
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别名
- MIB1
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背景
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This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
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分子量
- 110 kDa
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基因ID
- 57534
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UniProt
- Q86YT6
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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