TCF4 抗体 (AA 518-667)
Quick Overview for TCF4 抗体 (AA 518-667) (ABIN5542392)
抗原
See all TCF4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 518-667
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原理
- TCF4 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human TCF4 (AA: 518-667) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TCF4 (Transcription Factor 4 (TCF4))
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别名
- TCF4
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背景
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This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.
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分子量
- 71.3 kDa
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基因ID
- 6925
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UniProt
- P15884
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途径
- WNT signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
抗原
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