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PKN1 抗体 (AA 442-620)

PKN1 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4H10B1 unconjugated
产品编号 ABIN5542353
发货至: 中国
  • 抗原 See all PKN1 抗体
    PKN1 (Protein Kinase N1 (PKN1))
    抗原表位
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 442-620
    适用
    • 30
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 20
    • 10
    小鼠
    克隆类型
    • 21
    • 9
    单克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PKN1 antibody is un-conjugated
    应用范围
    • 16
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    原理
    PKN1 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human PKN1 (AA: 442-620) expressed in E. Coli.
    克隆位点
    4H10B1
    亚型
    IgG2b
    Top Product
    Discover our top product PKN1 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    PKN1 (Protein Kinase N1 (PKN1))
    别名
    PKN1 (PKN1 产品)
    背景
    The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
    分子量
    104 kDa
    基因ID
    5585
    UniProt
    Q16512
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