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PKN1 抗体 (AA 442-620)

This anti-PKN1 antibody is a 小鼠 单克隆 antibody detecting PKN1 in ELISA, IHC, ICC 和 FACS. Suitable for 人.
产品编号 ABIN5542353
发货至: 中国

Quick Overview for PKN1 抗体 (AA 442-620) (ABIN5542353)

抗原

See all PKN1 抗体
PKN1 (Protein Kinase N1 (PKN1))

适用

  • 34
  • 7
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 23
  • 11
小鼠

克隆类型

  • 24
  • 10
单克隆

标记

  • 20
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This PKN1 antibody is un-conjugated

应用范围

  • 20
  • 7
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

4H10B1
  • 抗原表位

    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 442-620

    原理

    PKN1 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human PKN1 (AA: 442-620) expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    PKN1 (Protein Kinase N1 (PKN1))

    别名

    PKN1

    背景

    The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

    分子量

    104 kDa

    基因ID

    5585

    UniProt

    Q16512
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