HDAC4 抗体 (AA 456-592)
Quick Overview for HDAC4 抗体 (AA 456-592) (ABIN5542325)
抗原
See all HDAC4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 456-592
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原理
- HDAC4 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human HDAC4 (AA: 456-592) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- HDAC4 (Histone Deacetylase 4 (HDAC4))
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别名
- HDAC4
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背景
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
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分子量
- 119 kDa
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基因ID
- 9759
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UniProt
- P56524
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
抗原
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